摘要
目的探讨明胶海绵颗粒与Embosphere生物微球栓塞治疗原发性肝癌破裂出血的效果。方法回顾分析近5年来收治的49例(使用明胶海绵23例,使用Embosphere生物微球26例)经导管肝动脉明胶海绵和Embosphere生物微球栓塞治疗的原发性肝癌破裂出血患者的临床资料,评价即时止血和再次出血率。结果明胶海绵组和Embosphere生物微球组即时止血率均为100%;在明胶海绵栓塞治疗后7天内再次出血率为13.0%(3/23),1例转外科手术,1例再次介入治疗,术后成功止血,1例因突发失血性休克死亡;在Embosphere生物微球栓塞后7天内再次出血率为3.8%(1/26),显著低于明胶海绵组(P<0.01)。结论明胶海绵和Embosphere生物微球治疗肝癌破裂出血即时止血效果相同,但Embosphere生物微球治疗术后再出血风险明显减少。
Objective To explore the efficacy of the gelatin sponge particle and embosphere microsphere embolization for the treatment of patients with hepatocellular carcinoma and tumor rupture. Methods 49 patients with rupture of hepatocellular carcinoma underwent transcatheter arterial embolization by gelatin sponge particle （n =23） or embosphere microsphere （n =26） embolization in recent 5 years,and instant hemostatic and rehaemorrhagia rates were compared. Results There was no difference between gelatin sponge particle and embosphere microsphere embolization on the effects of instant hemostatie （both were 100% ）;Seven days after intervention,the rehaemorrhagia rate in gelatin sponge particles was 13.0%（3/23）,one patient was transferred to surgery,one patient was re-intervened and one patient dead because of haemorrhagic sbock,respectively;The rehaemorrhagia rate in embosphere microspheres group was 3.8%（1/26,P〈0.01）,and the patient received re- intervention and the bleeding was stopped successfully. Conclusion The instant hemostatie effect is the same between the gelatin sponge particle and embosphere microspheres embolization in patients with rupture of hepatoeellular carcinoma,however,the embosphere group has much less chance to rebleeding within 7 days.
出处
《实用肝脏病杂志》
CAS
2015年第6期651-654,共4页
Journal of Practical Hepatology
