摘要
目的:探讨肺康复对中重度慢性阻塞性肺疾病(COPD)患者抑郁、运动能力和肺功能的影响及抑郁与运动能力、肺功能的相关性。方法:38例患者于治疗前、治疗6个月后分别采用流调用抑郁自评量表(CES-D)和6 min步行试验(6MWT)、肺功能测定(FEV1%预计值和FEV1/FVC)对各组患者进行疗效评定。结果:治疗前后抑郁评分23.94±4.86 vs.14.66±2.47,P=0.000。6 min步行距离、FEV1%预计值分别为(353.6±27.90)m vs.(276.8±30.95)m,P=0.000;58.09±8.77 vs.58.34±7.94,P>0.05。抑郁评分与运动能力康复后显著改善。肺康复对肺功能没有改善。结论:肺康复可以减轻中重度COPD患者的抑郁、增加运动耐力,但抑郁与运动能力、FEV1%无明显相关性。
Objective To investigate the effects of pulmonary rehabilitation （PR） on the depression and exercises capacity and pulmonary function in elderly patients with stable moderate-to-severe chronic obstructive pulmonary disease. Methods 38 participants [（68.01 ± 5.27） years old; moderate 28, severe 10] were en- rolled in a 6-month PR program with exercise training. Subjects measurements were made of the Epidemiologic Studies Depression scale （CES-D）, 6-minute walk test （6MWT） and puhnonary function. Result The CES-D Scores before and after PR were 23.94 ± 4.86 vs. 14.66 ± 2.47, P = 0.000; 6 MWT and the percent of the predicted FEV1 before and after PR were （353.6 ±27.90）m vs. （276.8 ± 30.95）m, P = 0.000, 58.09 ± 8.77 vs. 58.34 ±7.94, P 〉 0.05. CES-D scores and exercise capacity improved after PR. But PR contributes nothing to the improvement of pulmonary function. Conclusion Although the PR improves the depression and exercise capacity in elderly patients with stable moderate-to-severe COPD, no statistically significant correlation was ob- served between depression scores and 6MWD and the percent of the predicted FEV1.
出处
《实用医学杂志》
CAS
北大核心
2015年第19期3159-3161,共3页
The Journal of Practical Medicine
基金
河南省卫生厅科技攻关项目(编号:200903138)
关键词
慢性阻塞性肺疾病
肺康复
抑郁
运动能力
Chronic obstructive pulmonary disease
Pulmonary rehabilitation
Depression
Exercise capacity
