摘要
目的:优选复方活血巴布膏中水煎药材的絮凝工艺。方法:以续断中的川续断皂苷Ⅵ保留率及沉降百分率为考察指标,采用星点设计-效应面法对水煎药材絮凝工艺进行研究。结果:壳聚糖絮凝沉淀法的最佳工艺条件为药液比1∶1.7,絮凝温度51℃,壳聚糖加入量为21.8m L(每100m L药液),p H值为5.6。结论:壳聚糖絮凝法沉降效果好,经济实用,优选的絮凝工艺合理、稳定可行,可用于复方活血巴布膏水提药材的絮凝澄清。
Objective：To optimize chitosan flocculation of water extraction in Fufang Huoxue Cataplasm.Methods：The central composite design-response surface methodology was applied to optimize the boiling water flocculation process with indexes of Asperosaponin Ⅵ retention in Dipsacus and percentage settlement.Results：Optimal condition of chitosan flocculation sedimentation method was that the mass concentration of liquid was 1：1.7,the flocculation temperature is 51℃,and the addition amount of chitosan was 21.8mL（each 100 mL liquid）,pH=5.6.Conclusion：Effect of chitosan flocculation is economical and practical.Preferred extraction process is reasonable,stable and viable,which could be used for flocculation of water extraction in Fufang Huoxue Cataplasm.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第10期3680-3683,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
山东省自主创新成果转化重大专项(No.2012ZHZX1C0405)
山东大学科技计划(No.201219008)
山东大学青年科技明星计划(No.20120142)~~
关键词
复方活血巴布膏
星点设计-效应面法
壳聚糖
川续断皂苷Ⅵ
絮凝沉降法
工艺优化
Fufang Huoxue Cataplasm
Central composite design-response surface methodology
Chitosan
Asperosaponin VI
Flocculation sedimentation method
Process optimization
