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TNF-β联合IL-6检测对早期诊断非小细胞肺癌术后放疗导致的放射性肺炎的初探 被引量：6

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摘要 目的探讨TNF-β联合IL-6检测对早期诊断放射性肺炎(RP)的价值,以利于临床上早期发现RP,进而有利于早期治疗的开展。方法回顾性分析本院收治的27例非小细胞肺癌术后联合放疗的患者血清TNF-β、IL-6以及相关补体水平,对照组20例,均为非小细胞肺癌术后未予联合使用化疗的患者,收集其术后血清TNF-β、IL-6以及相关补体水平相关数值资料,观察组27例,收集其放疗前及放疗后3天、两周及30天对应的血清血清TNF-β、IL-6以及相关补体水平相关数值资料,并尤其关注放疗导致的RP的患者血清相应的参数水平,比较术后放疗病人血清TNF-β和IL-6相比于对照组的差异,分析RP患者血清TNF-β和IL-6水平是否存在时间依赖性,同时关注TNF-β、IL-6联合的诊断价值。结果非小细胞肺癌患者术后联合使用放疗相比于对照组可显著上调TNF-β和IL-6水平,并存在一定的时间依赖性,TNF-β联合IL-6相比于单独TNF-β或IL-6检测有利于发现早期RP患者,进而有利于早期治疗。结论 TNF-β联合IL-6检测可作为早期诊断RP的潜在指标。
作者 梁文龙
机构地区 江苏省睢宁县人民医院肿瘤科
出处 《齐齐哈尔医学院学报》 2015年第26期3971-3973,共3页 Journal of Qiqihar Medical University
关键词 放射性肺炎 早期诊断 TNF-Β IL-6 补体
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献8

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二级参考文献46

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共引文献26

同被引文献49

引证文献6

二级引证文献45

齐齐哈尔医学院学报
2015年 第26期

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