摘要
目的探讨参附注射液治疗急性心肌梗死合并心力衰竭的临床效果。方法选取病历资料完整的心肌梗死合并心力衰竭患者64例,随机分为观察组及对照组各32例。2组患者均给予抗凝、扩血管、β-阻滞剂、ACEI、抗血小板、降脂及利尿等常规治疗,观察组在常规治疗的基础上联合参附注射液治疗。观察2组患者治疗前后心排血量(CO)、射血分数(LVEF)、血浆脑钠肽(BNP)水平变化及治疗2周后临床疗效。结果观察组总有效率为68.75%,明显优于对照组的43.75%,2组比较差异有统计学意义(P<0.05);2组患者治疗后CO、LVEF和BNP均较治疗前改善,观察组各指标改善程度优于对照组,差异有统计学意义(P<0.05)。结论心肌梗死合并心力衰竭在常规治疗基础上联合参附注射液能有效降低患者BNP,改善CO和LVEF,进一步改善心功能。
Objective To investigate the clinical effect of the treatment of acute myocardial infarction （AMI ） with heart fail-ure by the treatment of acute myocardial infarction （AMI ） .Methods A total of 64 patients complete medical records of AMI patients complicated with heart failure ,were randomly divided into observation group and control group ,32 cases ,two groups of patients were given conventional anticoagulation ,vasodilation ,beta blockers ,ACE inhibitors ,antiplatelet therapy , lipid-lowering therapy and diuretic treatment ,observation group on the basis of conventional treatment combined with Shen Fu Injection in the treatment ,observe two groups before and after treatment in patients with cardiac output （CO ） ,shoot ejec-tion fraction （LVEF） ,plasma brain natriuretic peptide （BNP） levels and treatment 2 weeks after clinical curative effect .Re-sults In the observation group ,the total effective rate was 68 .75% ,significantly better than the control group （43 .75% ） , two groups of statistical significant （ P〈0 .05 ）;after treatment ,the patients in the two Group Co ,LVEF and BNP were com-pared with those before treatment improved ,observation group of each index is improved than that in the control group ,the difference is statistically significant （ P〈0 .05 ） .Conclusion AMI patients with heart failure in on the basis of convention-al treatment combined with Shen Fu injection can effectively reduce the levels of BNP in patients with ,the improvement in patients with CO and LVEF ,further improve the heart function .
出处
《吉林中医药》
2015年第9期901-903,共3页
Jilin Journal of Chinese Medicine
基金
张家口市科技项目(20142979)
关键词
急性心肌梗死
参附注射液
心力衰竭
益气固脱
回阳救逆
acute myocardial infarction
Shen Fu Injection
heart failure
tonify qi
back yang to save inverse
