摘要
目的卵巢早衰(POF)主要指的是卵巢功能的衰竭,其是有多种的原因所造成的,一般主要是发生在40岁以下的妇女。近年来,卵巢早衰的发病有逐年上升的趋势。目前,对卵巢早衰的病因和发病机制的认识还很不清楚。对于POF来说,其病因存在非常明显的特殊性,一般涉及到了遗传学以及免疫学或者是酶缺陷以及医源性因素等等,对其的发病的因素进行了解,无论是对其进行临床的治疗还是对其的预防以及防治都有着非常重要的作用。本文就POF的遗传学及相关因素做一综述。
Premature ovarian failure（POF）that is common among women under the age of 40 is a functional failure of the ovarian caused by a variety of factors. Idiopathic POF is the most common type. However,these patients usually have no definite cause.A small part of POF has special cause,involving genetics,immunology,gonadotropin recept or defects,enzyme deficiencies and iatrogenic factors. Understanding the cause of it will be helpful to prevent its occurrence and improve its clinical therapy.
出处
《中国优生与遗传杂志》
2015年第10期132-135,共4页
Chinese Journal of Birth Health & Heredity
