期刊文献+

静脉溶栓对急性脑梗死并脑微出血患者近远期预后的影响 被引量:9

在线阅读 下载PDF
导出
摘要 目的探讨静脉溶栓对急性脑梗死并脑微出血患者近远期预后的影响。方法选取52例急性脑梗死合并脑微出血患者,随机分为对照组和研究组,各26例,对照组给予常规治疗,研究组在常规治疗基础上加用静脉溶栓治疗,记录两组患者治疗前、治疗2周、3个月后神经功能缺损变化情况。结果两组患者治疗前NIHSS评分差异无统计学意义(P>0.05),治疗2周后研究组NIHSS评分明显低于对照组(P<0.05)。治疗3个月后研究组mRS评分明显低于对照组(P<0.05)。结论对急性脑梗死合并脑微出血患者给予静脉溶栓治疗可显著改善其神经功能缺损情况,有利于保障患者近远期预后效果。
作者 刘秀君
出处 《河南医学研究》 CAS 2015年第8期75-76,共2页 Henan Medical Research
  • 相关文献

参考文献5

二级参考文献68

  • 1陈唯唯,漆剑频,肖明,宋金梅.CT灌注成像对超急性脑梗死半暗带两种判定方法的一致性研究[J].中国医学影像技术,2005,21(2):258-260. 被引量:32
  • 2冀瑞俊,贾建平,马欣,楚长彪.“病理生理窗”指导下的溶栓干预模式探讨[J].脑与神经疾病杂志,2007,15(2):89-91. 被引量:17
  • 3The National Institute of Netrological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischernic stroke. N Engt J Med, 1995, 333: 1581-1587.
  • 4Hacke W, Donnan G, Fieschi C, et al.ATLANTIS Trials Investigators; ECASS Trials Investigators; NINDS rt-PA Study Group Investigators. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet, 2004, 363: 768 -774.
  • 5Reeves MJ, Arora S, Broderick JP, et al; Paul Coverdell Prototype Registries Writing Group. Acute stroke care in the US: results from 4 pilot prototypes of the Paul Coverdell National Acute Stroke Registry. Stroke, 2005, 36: 1232-1240.
  • 6The NINDS t-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke, 1997, 28: 2109- 2118.
  • 7Hacke W, Kaste M, Fieschi C, etal. Rardomised double-blind placebocoutrolled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS H). Second European-Australasian Acute Stroke Study Investigators. Lancet, 1998, 352: 1245-1251.
  • 8Kase CS, Furlan AJ, Wechsler LR, et al. Cerebral hemorrhage after intra-arterial tbrombolysis for ischemic stroke: the PROACT Ⅱ trial. Neurology, 2001,57: 1603-1610.
  • 9Lame V, von Kummer R R, Muller A, et al. Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasrninogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS Ⅱ). Stroke, 2001,32: 438-441.
  • 10Clark WM, Wissman S, Atbers GW, et al. Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. JAMA, 1999, 282: 2019-2026.

共引文献46

同被引文献56

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部