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乌鲁木齐市维吾尔族青年与老年女性血清微量元素及骨密度的对比 被引量:5

Comparison of bone mineral density and serum trace elements between Uygur young and elderly women in Urumqi
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摘要 背景:雌激素通过影响骨骼细胞的新陈代谢而促进微量元素在骨骼中的储存,影响骨密度的变化。目的:比较乌鲁木齐市维吾尔族青年女性与老年女性骨密度及血清中微量元素的差异。方法:使用MEDILINK生产的双能X射线骨密度测量仪对乌鲁木齐市维吾尔族30-40岁(青年女性组)与60-70岁(老年女性组)女性各30人进行骨密度测定;使用美国贝克曼库尔特生产的Unicel Dxc 800 Synchron生化检验仪查血清中的微量元素钙、磷、镁、铁、铜、锌含量。比较不同年龄段女性血清中微量元素及骨密度水平。结果与结论:维吾尔族青年女性组骨密度显著高于老年女性组(P<0.001);维吾尔族青年女性组血清微量元素锌显著低于老年女性组(P<0.001);其余的血清微量元素钙、磷、镁、铁、铜两组之间差异无显著性意义(P>0.05)。结果表明维吾尔族女性不同年龄段骨密度随体内血清中部分离子元素的改变有较大的改变。 BACKGROUND: Estrogen promotes the storage of trace elements in the bones and thereby impacts the variation of bone mineral density through influencing the bone cell metabolism. OBJECTIVE: To study the difference of bone mineral density and serum trace elements between Uygur young and elderly females from Urumqi. METHODS: The bone mineral density was measured in the Uygur women aged 30 to 40 years and 60 to 70 years in Urumqi by dual-energy X-ray absorptiometry made in MEDILINK. The serum levels of trace elements, including calcium, phosphorus, magnesium, iron, copper, zinc, were measured by Unicel Dxc 800 Synchron biochemical test instrument produced by Beckman Kurt, USA. Serum levels of trace elements and bone mineral density were compared between two groups. RESULTS AND CONCLUSION: Compared with the elderly group, the bone mineral density was significantly higher but the serum level of zinc was lower in the young group (both P 〈 0.001 ). There were no differences in the other trace elements between the two groups (P 〉 0.05). These findings indicate that the bone mineral density of Uygur women at different age is significantly correlated with a part of trace elements in serum.
出处 《中国组织工程研究》 CAS 北大核心 2015年第33期5264-5268,共5页 Chinese Journal of Tissue Engineering Research
基金 新疆医科大学科研创新基金(XJC2012116)~~
关键词 骨密度 骨质疏松 组织构建 骨组织工程 微量元素 Bone density Osteoporosis Zinc
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