摘要
目的:观察中药制剂联合维生素D3(Vit D3)预防毛细支气管炎后喘息的临床效果。方法:将确诊为毛细支气管炎的住院患儿107例,按随机数字表分成治疗组54例和对照组53例。治疗组给予口服中药和Vit D3,中药制剂[黄芪、党参、白术、茯苓、(西)防风、甘草]每日1剂,分2次服用,每月服10 d,Vit D3400 U/d,均连服3个月;对照组给予吸入丙酸氟替卡松气雾剂。随访1年,统计两组发生喘息性疾病的病例数、发作次数、出院后1年行肺功能检测。结果:1年内对照组发生喘息24例(45.28%),治疗组发生喘息14例(25.92%),两组比较差异有统计学意义(P<0.05);治疗组潮气量、达峰时间比、达峰容积比、25%呼气流速等肺功能指标明显改善,与对照组比较差异有统计学意义(P<0.05)。结论:中药联合维生素D3治疗能改善毛细支气管炎后气道阻塞、预防反复喘息等症状,疗效确切,值得临床推广应用。
Objective： To study the effects of Traditional Chinese medicine and vitamin D3（ Vit D3） in preventing bronchiolitis wheezing. Methods： One hundred and seven children diagnosed with capillary bronchitis were randomly divided into treatment group（ 54cases） and the control group（ 53 cases）. The treatment group was given traditional Chinese medicine combined with vitamin D3： The traditional Chinese medicine（ Astragalus,Codonopsis,Atractylodes,Poria cocos,Chinese parsnip root,Licorice） were given daily 1agent,twice per day,10 days each month. Vit D3400 units per day,all children were given three months,and the control group inhaled the fluticasone propionate aerosol. One year’s follow-up,counted up the number of children with asthmatic diseases,episodes,and tested lung function after discharging from hospital one year later. Results： There were 24 cases（ 45.28%） of asthmatic breath occurred in control group within a year,in the treatment group were 14 cases（ 25. 92%）（ P 〈 0. 05）. The lung function index,such as tidal volume,peak time,peak volume ratio,ratio of 25% expiratory flow were improved obviously in treatment,and had great difference compared with the control group（ P〈0.05）. Conclusion： Traditional Chinese medicine combined with vitamin D3 therapy can improve the capillary bronchitis airway obstruction,prevent symptom such as wheezing,has curative effect,it is worthy of clinical application.
出处
《儿科药学杂志》
CAS
2015年第10期23-26,共4页
Journal of Pediatric Pharmacy
基金
广西玉林市科学研究与技术开发计划项目课题
编号13036025
关键词
中药
维生素D3
毛细支气管炎
喘息
Traditional Chinese medicine
Vitamin D3
Bronchitis
Wheezing
