摘要
目的 对青年男性血脂异常患者勃起功能障碍（ED）的危险因素进行分析.方法 入选2006年9月至2011年8月于北京安贞医院住院的青年患者242例,根据血脂水平分为血脂异常组（136例）和血脂正常组（106例）,采用国际勃起功能问卷表-5（IIEF-5）对患者近6个月的性生活质量进行评分.比较2组患者ED发生情况,比较ED和勃起功能正常患者相关临床资料差异.结果 血脂异常组IIEF-5评分高于血脂正常组[（19±4）分比（22±4）分],差异有统计学意义（t=-5.429,P＜0.01）.血脂异常组ED发生率高于血脂正常组,差异有统计学意义[55.9％（76/136）比26.4％ （28/106）] （x2=21.107,P＜0.01）.ED患者年龄、吸烟比例、体重指数高于勃起功能正常者[（42±3）岁比（39±5）岁、59.6％（62/104）比44.9％（62/138）、（26.0±3.1）kg/m2比（25.1 ±2.9） kg/m2] （P ＜0.05）;多因素Logistic回归分析结果显示：年龄、吸烟和血脂异常是青年ED的独立危险因素（比值比1.255、1.874、4.399,P＜0.05）.结论 青年男性ED与血脂异常密切相关,吸烟和年龄是重要的危险因素.
Objective To investigate the risk factors of erectile dysfunction （ED） in young man with dyslipidemia.Methods Totally 242 young man from September 2006 to August 2011 were enrolled and divided into dyslipidemia group （136 cases） and normal lipid group （106 cases）.The intenational index of erectile function 5 （IIEF-5） was used to assess the sexual quality of life in recent 6 months and the incidenc of ED was obtained and compared between the two groups.The clinical data of subjects with ED and normal erectile function were compared.Results IIEF-5 scores in dyslipidemia group was significantly lower than that in normal lipid group [（19 ±4） scores vs （22 ±4） scores] （t =-5.429,P 〈0.01）.The incidence of ED dyslipidemia group was significantly higher than that in normal lipid group [55.9% （76/136） vs 26.4% （28/106）] （x2 =21.107,P 〈0.01）.The ED patients had older age,higher smoking rate and body mass index compared with those with normal erectile function [（42 ±3） years vs （39 ±5） years,59.6% （62/104） vs 44.9% （62/138）,（26.0 ± 3.1） kg/m2 vs （25.1 ± 2.9） kg/m2] （P 〈 0.05）.Logistic multivariable regression analysis showed that age,smoking and dyslipidemia are independent risk factors of ED in young man （OR =1.255,1.874,4.399,P 〈 0.05）.Conclusion ED and dyslipidemia are closely related,age and smoking are the important risk factorsin young man.
出处
《中国医药》
2015年第9期1347-1349,共3页
China Medicine
