摘要
目的 探讨新疆地区内镜黏膜下剥离术（ESD）治疗早期胃癌及癌前病变的价值。方法 对2008年6月-2013年12月我科收治的106例经ESD治疗的早期胃癌及癌前病变患者的临床资料进行分析,并与同期在我院经外科手术治疗的73例早期胃癌患者的临床资料进行对比分析。结果 106例行ESD治疗患者均在内镜下成功切除病灶,一次性整块切除率、一次性完整切除率及组织学完整治愈率分别为100.0%、97.2%和97.2%。术中穿孔和术后出血发生率均为0.9%,均经内镜下成功处理,无与ESD手术相关死亡发生。在早期胃癌的手术治疗上,与常规外科手术治疗相比,ESD组手术时间、住院时间明显缩短（P〈0.05）,术后出血发生率及住院费用显著降低（P〈0.05）。两组在术后狭窄发生率及复发率方面未见明显差异（P〉0.05）。结论 ESD在治疗早期胃癌及癌前病变中创伤小、并发症少、安全可靠,适合新疆地区广泛开展应用。
Objective To discuss the value of endoscopic submucosal dissection （ESD） for the treatment of early gastric cancer and precancerous lesion in Xinjiang area.Methods Analysis was made in the clinical data of 106 patients receiving ESD treatment of early gastric cancer and precancerous lesion between December 2008 and June 2013. Comparison was made with the clinical data of 73 patients with early gastric cancer treated by conventional surgeries at the same period. Results The focuses of 106 patients treated by ESD were all resected successfully. The one-time resection rate of whole piece, the one-time complete resection rate, and the histologicaUy complete healing rate were 100.0 %, 97.2%, and 97.2%. The incidences of intraoperative perforation and postoperative bleeding were both 0.9%. All these symptoms were successfully treated under endoscopy. There was no ESD related death occurred. Compared with the indexes in the group treated by conventional surgeries, the operative time and the hospital stay in the ESD group were significantly shorted （P 〈 0.05）, and the incidence of postoperative bleeding and the cost were significantly lowered （P 〈 0.05）. There was no difference in the incidence of postoperative stenosis and the recurrence rate between the two groups （P 〉 0.05）.Conclusion ESD for early gastric cancer has the advantages of small trauma, less complications, safety, and reliability. It is suitable for the general application in Xinjiang area.
出处
《西南国防医药》
CAS
2015年第9期957-959,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
内镜黏膜下剥离术
早期胃癌
癌前病变
外科手术
endoscopic submucosal dissection
early gastric cancer
precancerous lesion
surgery
