摘要
先天性膈疝(CDH)是膈肌异常伴随肺发育不良(PH)、新生儿持续肺动脉高压(PPHN)等病理、生理改变的先天性疾病,其发病率、病死率均较高。迄今为止,CDH的具体病因、最佳治疗措施及预后影响因素均未阐明,这使得CDH的诊治具有挑战性。近年由于医学技术的不断进步、各种治疗措施的不断改进,CDH患儿的存活率有所提高。然而,CDH存活患儿的长期跟踪随访,尚需引起临床医师的足够重视,包括如何改善其预后、提高生活质量等。笔者拟就CDH的最新诊治进展,进行综述如下。
Congenital diaphragmatic hernia（CDH）is an uncommon congenital anomaly of the diaphragm with pulmonary hypoplasia（PH）and persistent pulmonary hypertension as serious consequences（PPHN）.Till now,the etiopathogenisis and best treatment strategies are still largely unknown,and practice strategies vary widely among different centres,so CDH still remains a challenging condition.In recent years,with the development of medical technology and improvement of treatment,survival rates of CDH patients appear to have increased.Survivors have been shown to be at risk for many long-term morbidities,so the importance of long-term follow-up of CDH survivals should be highlighted,including long-term prognosis and quality of life.This research focuses on the progress research of current diagnosis and treatment of CDH.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2015年第4期530-534,共5页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家自然科学基金青年科学基金项目(81300238)~~
关键词
疝
横膈
病因
诊断
治疗
预后
随访研究
Hernia
diaphragmatic
Pathogenesis
Diagnosis
Treatment
Prognosis
Follow-up studies
