摘要
目的：建立1-12岁儿童静脉血血常规正常参考值范围。方法对526例1-12岁儿童静脉血进行血常规检测,将研究对象按年龄分组,对各项参数做统计学分析,得出各项参数的参考值范围。结果按年龄分4组,除白细胞（WBC）计数和WBC 分类外,其余各项检验结果差异无统计学意义（P〉0.05）,合并后得到 RBC：（4.02-5.2）×10^12/L,HGB：108-144 g/L, Hct：35.2%-40.4%,MCV：74.6-89.9 fL,MCH：20.9-34.7 pg,MCHC：332-340 g/L,PLT：（157-409）×10^9/L。WBC 除6-〈9岁、9-12岁差异无统计学意义（P〉0.05）,其余各组间差异有统计学意义（P〈0.05）,经合并后得到1-〈3岁组：（4.88-13.38）×10^9/L,3-〈6岁组：（4.26-11.6）×10^9/L,6-12岁组：（4.24-10.24）×10^9/L。WBC 分类结果在不同年龄段差异有统计学意义（P〈0.05）,1-岁 NE：29%-32%,LY：58%-61%；3-〈6岁组 NE：43%-46%,LY：43%-46%；6-〈9岁组 NE：49%-52%,LY：38%-40%；9-12岁组 NE：51%-58%,LY%：33%-39%。结论除 WBC 计数和分类,其余参数在各年龄组之间无明显差异,WBC 计数和分类在不同年龄阶段差异有统计学意义（P〈0.05）,WBC 计数随年龄递增而递减,中性粒细胞百分比随年龄增加呈上升趋势,而淋巴细胞百分比则随之下降。建议在日常检验工作中按照不同年龄和项目合理建立不同的参考范围。
Objective To determine normal reference ranges for venous blood count among children aging from 1 year old to 12 years old.Methods These normal reference ranges were defined in a population of 526 healthy children who had no blood system diseases,allergic diseases,respiratory system diseases,urinary system diseases,digestive system disease,rheumatoid disease,thyroid disease,parasitic infections,malignancies and genetic disease,etc.Values of white blood cell count （WBC）,red blood cell count （RBC）,hemoglobin （Hb）concentration,red blood cell specific volume （Hct）,mean corpusular volume（MCV）,mean cell hemoglobin （MCH）,mean corpuscular hemoglobin（MCHC）,platelet （PLT）,percentage of neutrophil （NE%）,percentage of lymphocyte （LY%）,percentage of mononuclear cells （MO%）,percentage of acidophilic granulocyte （EOS%）.Statistical analysis was done on various parameters that we recorded,and then for every parameter,we could get the various reference ranges for different age groups.Results The subjects were divided into 4 groups based on age.Besides the parameters of WBC count and classification of WBC,the rest of parameters were proved to be of no statistical difference between 4 groups..After an integration of the values,we could get the results as follows：RBC（4.02-5.2）×10 ^12/L,HGB 108-144 g/L,Hct 35.2%-40.4%,MCV 74.6-89.9 fL,MCH 20.9-34.7 pg,MCHC 332- 340 g/L,PLT（157 - 409 ）×10^9/L.WBC count did not have statistical difference between the age group 6-〈9 and 9-12,but did have between the rest groups.After an integration of the values of WBC count,it could be conclu-ded that WBC count of age group1-〈3 was（4.88-13.38）×10 ^9/L,that of age group 3-〈6 was（4.26-1 1.6）×10^ 9/L and that of age group 6-12 was （4.24-10.24）×10^ 9/L.WBC classification results were various in different age groups.The values showed as follows：age group 1-〈3 NE：29%-32%,LY：58%-61%;age group 3 -〈6 NE：43%-46%,LY：43%-46%;age group 6-〈9NE：49%-52%,LY：38%-40%;age group 9 to 12NE：5 1% - 58%,LY：33% - 39%.Conclusion WBC classification results and WBC count do have statistical difference in different age groups.Besides the parameters of WBC count and classification of WBC,the rest of parameters are proved to be of no statistically difference in different age groups.The values of WBC count decreases as the age increases.From WBC classification results,the most apparent fact is that the percentage of neutrophil increases as the age increases but the percentage of lymphocyte is just the contrary.As mentioned above,we suggest that we should establish a specific whole blood count normal reference range for each age group during our laboratory testing work.
出处
《国际检验医学杂志》
CAS
2015年第16期2332-2334,共3页
International Journal of Laboratory Medicine
关键词
儿童
静脉血
血常规
正常参考范围
children
venous blood
routine blood test
normal reference range
