摘要
目的:探讨六味地黄汤治疗老年2型糖尿病肾病的临床疗效。方法:将120例老年2型糖尿病肾病患者随机等分为对照组和治疗组。对照组予以常规西医治疗,治疗组在对照组治疗的基础上加用六味地黄汤。两组均治疗3个疗程后统计临床综合疗效,并观察两组治疗前后中医证候评分、空腹血糖(FBG)、餐后2 h血糖(PBG)、糖化血红蛋白(Hb Alc)、24 h尿白蛋白排泄率(UAE)、内生肌酐清除率(Ccr)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)。结果:治疗组患者临床综合疗效优于对照组(P<0.05)。治疗组治疗后中医证候评分、UAE、Ccr均低于对照组(P<0.05)。两组患者治疗前后FBG,PBG,Hb Alc,TC,TG,HDL-C及LDL-C经比较有统计学意义(P<0.05),两组治疗后各项经比较均无统计学意义(P>0.05)。结论:六味地黄汤治疗老年2型糖尿病肾病患者临床疗效确切。
Objective：To investigate the effect of Liuwei Dihuang decoction treatment of elderly type 2 diabetic nephropathy.Methods：120 elderly patients with type 2 diabetes nephropathy patients randomly divided into control group and treatment group.The control group received routine western medicine treatment,while the treatment group on the basis of control group therapy plus soup of Liuwei Dihuang flavour glutinous rehmannia .To observe the clinical treatment effect after 3 course,and to observe TCM syndrome score,fasting blood glucose （ FBG） ,2 h postprandial blood glucose （ PBG） ,glycosylated hemo-globin （HbAlc）,24 h urinary albumin excretion （UAE）,endogenous creatinine clearance rate （Ccr）,total cholesterol （TC）,triglyceride （TG）, high -density lipoprotein cholesterol （ HDL-C） and low density lipoprotein cholesterol （ LDL-C） of the two groups before and after treatment .Results：The treat-ment group patients clinical comprehensive curative effect was better than that of control group （P〈0.05）.The treatment group after treatment of TCM syn-drome score,UAE,Ccr were lower than the control group（P〈0.05）.Two groups of patients before and after treatment of FBG,PBG,HbAlc,TC,TG,HDL and LDL-C-C by comparison with statistical significance （P〈0.05）,but after treatment there was no statistical significance （P〉0.05） between two groups.Conclusion：Liuwei Dihuang decoction treatment clinical curative effect of elderly patients with type2 diabetic nephropathy.
出处
《护理实践与研究》
2015年第8期6-8,共3页
Nursing Practice and Research
关键词
糖尿病肾病
六味地黄汤
中药疗法
Diabetic nephropathy
Liuwei Dihuang decoction
Traditional Chinese medicine therapy
