摘要
目的探讨H型高血压颈动脉粥样硬化通心络联合阿托伐他汀治疗作用。方法选取2012年7月至2014年7月我院收治的112例H型高血压颈动脉粥样硬化患者作为研究对象,按照患者入院顺序分为对照组和治疗组,每组56例,对照组患者单纯给予阿托伐他汀治疗,治疗组在此基础上上联合通心络治疗,对两组治疗前后纤容酶原激活物变化情况、D-二聚体、颈动脉内膜中层厚度、hs-CRP(超敏C反应蛋白)等指标以及治疗效果进行比较。结果与治疗前相比,两组纤容酶原激活物变化情况、D-二聚体、颈动脉内膜中层厚度、超敏C反应蛋白等指标均有所改善,差异具有统计学意义(P<0.05),且治疗组改善情况与对照组相比,差异明显,具有统计学意义(P<0.05);治疗组总有效率98.2%明显高于对照组78.6%,两组间差异存在统计学意义(P<0.05)。结论 H型高血压颈动脉粥样硬化采用通心络联合阿托伐他汀治疗疗效确切,可显著改善血脂、凝血、纤维系统平衡情况,延缓颈动脉硬化临床进展时间,值得临床推广使用。
Objective To study the H tongxinluo hypertension carotid atherosclerosis with atorvastatin therapy effect. Methods July 2012-July 2014 of our hospital, 112 cases of H hypertensive patients with carotid atherosclerosis as the research object, according to the order of patients admitted to hospital were divided into control group and treatment group, 56 cases in each group, control group patients simply given atorvastatin treatment, treatment group on the basis of this up and combined therapy with tongxinluo the two groups before and after treatment plasminogen activator capacity fiber changes, D-dimer, carotid intima-media thickness, hs-CRP（high-sensitivity C-reactive protein）, and other indicators, and therapeutic effects were compared. Results Compared with before treatment, two groups of fiber volume enzyme changes the original activators, D-dimer, carotid intima-media thickness, hypersensitive c-reactive protein and other indicators are improved, statistically significant difference（P 0.05）, and improve treatment group compared with control group, the difference to be markedly, with statistical significance（P 0.05）. Treatment group, the total efficiency of 98.2% was significantly higher than 78.6%, differences between the two groups was statistically significant（P 0.05）. Conclusion H hypertension carotid atherosclerosis with tongxinluo with atorvastatin therapy curative effect, can significantly improve the blood lipid, blood coagulation, fiber system balance situation, clinical progress of time, delay the carotid atherosclerosis is worth clinical use.
出处
《中国医药指南》
2015年第23期10-11,共2页
Guide of China Medicine
