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血尿酸监测在肺源性心脏病患者中的应用价值 被引量:4

Application value of monitoring the blood uric acid in patients with cor-pulmonale
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摘要 目的探讨监测血尿酸水平在慢性肺源性心脏病患者中的临床应用价值。方法选取我院呼吸内科收治的96例慢性肺源性心脏病患者为患者组,其中代偿期患者45例,失代偿期患者51例。选择同期来我院健康体检者45例为对照组。检测两组受试者血尿酸水平,并检测观察组患者血氧分压、脑钠肽水平,并对检测结果进行统计学分析。结果患者组患者血尿酸水平高于对照组,差异具有统计学意义(t=5.510,P=0.023);慢性肺源性心脏病患者失代偿期组血氧分压水平低于代偿期组,而脑钠肽、血尿酸水平高于代偿期组,且差异均有统计学意义(t=2.072、5.567、2.028,P均<0.05)。结论血尿酸水平的检测可用于慢性肺源性心脏病患者的诊断及疾病发展阶段的评估。 Objective To discuss the clinical application value of blood uric acid level in chronic pulmonary heart disease patients. Methods 96 cases pulmonary heart disease patients in Respiratory Medicine Department of our hospital were selected as observation group, including 45 cases compensated patients and 51 cases decompensated patients. In the same time, 45 cases healthy controls were selected in health examination center. The blood uric acid level was detected in two groups, and artery blood oxygen partial pressure and brain natriuretic peptide level were detected in observation group, all date were analyzed statistically.Results The level of blood uric acid in observation group is higher than control group, and the difference had statistical significance(t= 5.510,P= 0.023); The level of artery blood oxygen partial pressure in decompensated patients is lower than compensated patients, but the level of blood uric acid and brain natriuretic peptide in decompensated patients is higher than compensated patients, and the differences all had statistical significance(t= 2.072, 5.567, 2.028, Pall〈0.05). Conclusion The level of blood uric acid can be used in diagnosis of chronic pulmonary heart disease and assess the stage of the disease.
出处 《实用检验医师杂志》 2015年第2期109-111,共3页 Chinese Journal of Clinical Pathologist
关键词 血尿酸 脑钠肽 血氧分压 慢性肺源性心脏病 评价指标 Blood uric acid Brain natriuretic peptide Blood oxygen pressure Chronic pulmonary heart disease Evaluation index
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  • 1王瑜,陈曦,陈玉岚,高颖,木胡亚提.血清尿酸水平检测在慢性肺心病患者心衰严重程度评估中的预测价值[J].海南医学院学报,2013,19(11):1512-1514. 被引量:4
  • 2Harzand A, Tamariz L, Hare JM. Uric acid, heart failure survival, and the impact of xanthine oxidase inhibition. Congest Heart Fail, 2012 , 18 : 179-182.
  • 3Savarese G, Ferri C, Trimarco B, et al. Changes in serum uric acid levels and cardiovascular events: a meta-analysis. Nutr Metab Car- diovasc Dis, 2013,23 : 707-714.
  • 4Hamaguchi S, Furumoto T, Tsuchihashi-Makaya M, et al. Hyper- uricemia predicts adverse outcomes in patients with heart failure. Int J Cardiol,2011,151 : 143-147.

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