摘要
目的:探讨CA125在CIN患者宫颈、阴道分泌物中的表达水平与检测价值。方法:选取经活检确诊的CINI患者30例为组1,CINII患者25例为组2,CINⅢ患者23例为组3,选取健康查体的正常生育期妇女40例为组4,采用电化学发光免疫分析法检测4组研究对象的宫颈、阴道分泌物及血清CA125的表达水平。结果:CINⅢ患者宫颈、阴道分泌物CA125的表达水平均高于正常生育期妇女(P>0.05),差异有统计学意义(P<0.01)。结论:CINⅢ患者宫颈、阴道分泌物CA125的表达水平比血清CA125更为敏感,应用宫颈、阴道分泌物CA125检测能提高CINⅢ的检出率。
Objective： To investigate t CA125 expression in the cervical and vaginal secretions and explore its clinical values.Methods： 78 cases of CIN patients confirmed by biopsy were divided into 3 groups（ CINI 30 cases,CINII 25 cases,CINIII 23 cases）,and a total of 40 women in normal child-bearing period were selected as group 4. The CA125 levels in the cervical secretion,vaginal secretion and serum of the four groups were detected by automatic electro-chemiluminescent immunoassay. Results： The CA125 levels in the cervical secretion and vaginal secretion of of CINIII patients were higher than those of the women in normal child-bearing period,and the differences were statistically significant（ P〈0. 001）. Conclusions： The CA125 expression of cervical secretions and vaginal secretions is more sensitive than serum. The detection of cervical and vaginal secretions CA125 could improve the detection rate of CINIII.
出处
《中国民康医学》
2015年第13期11-12,27,共3页
Medical Journal of Chinese People’s Health
关键词
CA125
宫颈分泌物
阴道分泌物
CIN
CA125
Cervical secretion
Vaginal secretion
CIN patients
Women in normal child-bearing period
