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抗菌手术薄膜在预防神经外科手术部位感染效果研究 被引量:8

Effect of antimicrobial-impregnated incise drape on preventing surgical site infection following neurosurgical operation
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摘要 目的了解抗菌手术薄膜对降低神经外科患者手术部位感染(SSI)的效果。方法将2012年1—12月某院神经外科病变手术患者分为使用抗菌手术薄膜组(A组)和普通手术薄膜组(B组),比较两组患者术后SSI发生率,并进行危险因素分析。结果A组患者术中手术切口薄膜起边率为38.3%(98/256),低于B组的96.88%(248/256),两组患者薄膜起边率比较,差异有统计学意义(χ2=200.57,P<0.01)。512例患者,发生SSI17例,发生率为3.32%,A组患者SSI发生率为1.56%(4/256),低于B组的5.08%(13/256)(χ2=7.93,P<0.05)。神经外科SSI高危因素多因素分析结果表明,体重指数(BMI)≥24、出现围手术期低体温、吸烟、术前住院日数≥5 d,以及未使用抗菌手术薄膜均是神经外科SSI独立危险因素。结论神经外科手术中是否使用抗菌手术薄膜是神经外科SSI的独立危险因素之一;使用抗菌手术薄膜能有效降低起边率和SSI发生率,建议在神经外科手术中使用。 Objective To investigate the effect of antimicrobial-impregnated incise drape on preventing surgical site infection(SSI)following neurosurgical operation.Methods Patients undergoing neurosurgical operation from January to December 2012 were divided into two groups:antimicrobial-impregnated incise drape group(group A)and general incise drape group(group B).The occurrence of SSI and risk factors for SSI were analyzed.Results Percentage of drape lifting at the wound edge in group A was lower than group B(38.3%[98/256]vs 96.88% [248/256],χ^2=200.57,P〈0.01).Among512 patients,SSI rate was 3.32%(n=17),SSI rate in group A was lower than group B(1.56%[4/256]vs 5.08%[13/256],χ^2=7.93,P〈0.05).Multivariate analysis revealed that body mass index≥24,perioperative hypothermia,smoking,perioperative length of hospital stay≥5 days,and lack of drape use were independent risk factors for SSI following neurosurgical operation.Conclusion Whether antimicrobial-impregnated incise drape is used in neurosurgical operation is one of the independent risk factors for SSI following neurosurgical operation,it can effectively reduce the drape lifting rate and incidence of SSI,and is recommended to be used in neurosurgical operation.
出处 《中国感染控制杂志》 CAS 北大核心 2015年第6期389-392,共4页 Chinese Journal of Infection Control
关键词 神经外科 抗菌手术薄膜 手术部位感染 医院感染 neurosurgery antimicrobial-impregnated incise drape surgical site infection healthcare-associated infection
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