摘要
系统性红斑狼疮是一种累及多系统、多器官并出现多种自身抗体的自身免疫性疾病,其发病机制目前尚不完全清楚,多认为是遗传因素和环境因素共同作用的结果。在环境因素中,感染被认为是影响系统性红班狼疮病情活动和导致死亡的最常见原因之一,因此有效的预防和治疗,对改善患者预后至关重要。本文就感染与系统性红斑狼疮关系的研究进展作一综述。
Systemic lupus erythematosus ( SLE ) is an autoimmune disease characterized by widespread immune dysregulation and the hyper-production of multiple autoantibodies and immune complexes, involving variety of organs. The etiology of SLE is still not entirely clear. It impacted by genetic factors and environmental factors. Infection is a major cause of mortality in systemic lupus erythematosus,so the effective prevention and treatment is essential for improving the prognosis of patients. The literature concerning the relationship between infection and SLE was reviewed in this paper.
出处
《皮肤病与性病》
2015年第3期153-156,共4页
Dermatology and Venereology
基金
云南省卫生科技计划项目编号:2014 NS 115 项目名称:自身免疫性皮肤病合并侵袭性真菌感染的临床及致病的研究