摘要
目的:探究抗肿瘤药物不良反应,为临床安全合理用药提供依据。方法:选择肿瘤患者85例分为两组。观察组45例患者采用卡培他滨进行治疗;对照组40例患者则采用培美曲塞进行治疗。观察两组患者不良反应及其累及的系统器官情况。结果:观察组患者的血小板减少、腹泻以及头晕头痛等不良反应的比例较对照组有所减少;观察组产生不良反应所累及的消化系统、血液系统以及神经系统等均少于对照组,差异具有统计学意义(P<0.05)。结论:卡培他滨可以减少肿瘤患者不良反应的发生率,对患者的系统器官累及相对较轻;在临床上应对抗肿瘤药物所引发的不良反应引起重视,定期检测报告,为临床提供有意义的参考资料,减少不良反应的发生。
Objective To explore the adverse reaction of anti tumor drugs,provide the basis for clinical use of the drug.Methods Select 85 cases of cancer patients and divided into 2 groups.In 45 cases of the observation group were treated by capecitabine treat-ment,control group patients were treated with Pemetrexed,observe organ systems and statistical of 2 groups of patients with adverse re-actions and involving the situation.Results The adverse reactions of patients in observation group were thrombocytopenia,diarrhea, dizziness and headache proportion lower than control group;the observation group has an adverse reaction in the digestive system, blood system,nervous system and other organs was less than in the control system of the proportion of group involvement,with statisti-cally significant difference between the 2 groups （P 〈0.05）.Conclusion Capecitabine can reduce the incidence of adverse reaction of tumor patients,the system organ involvement in patients with relatively small;be against adverse responses induced tumor drug atten-tion in clinical,regular inspection report,to provide a meaningful reference for the clinical,avoid adverse reactions occur.
出处
《中国民族民间医药》
2015年第10期53-54,共2页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
抗肿瘤药物
卡培他滨
不良反应
Antitumor drugs
Capecitabine
Adverse reaction
