摘要
目的 探讨化疗期癌症患者癌因性疲乏与生命质量的关系。方法 采用便利抽样方法,使用一般情况调查表、癌症疲乏量表（cancerfatigue scale,CFS）、癌症治疗功能评价量表（functional assessment of cancer therapygeneral,FACT-G）对2014年1月～6月于肿瘤内科住院化疗的癌症患者进行调查。结果 回收有效问卷105份。本次调查中,以男性（60.00%）、已婚（95.24%）、初中（36.19%）、农村（38.10%）、农保（52.38%）、消化系统肿瘤患者（56.19%）、美国东部肿瘤协作组（eastern cooperative oncology group,ECOG）评分1分（94.29%）居多。CFS总分为（21.24±7.76）分,总分及各维度与FACT-G量表总分及各维度均呈负相关（均有P〈0.05）。多元线性回归分析结果显示,CFS的3个维度均进入方程（均有P〈0.05）,按照标准化回归系数将自变量对生命质量的贡献大小排序,依次为：躯体疲乏、情感疲乏和认知疲乏。结论 化疗期癌症患者癌因性疲乏发生率高,会导致患者生命质量的下降。提示降低患者的癌因性疲乏水平,有助于改善其生命质量。
Objective To explore the relationship between cancer-related fatigue and quality of life in cancer patients with chemotherapy. Methods Cancer patients with chemotherapy at the First Affiliated Hospital of Anhui Medieakl University between January and June in 2014 were surveyed with questionnaires. Data regarding the cancer-related fatigue and quality of life were collected by the cancer fatigue scale （CFS） and the functional assessment of cancer therapygeneral version （FACT-G）. Results A total of 105 vipionaives were recruited. The majority of patients were men （60. 00% ） , married （95.24%）, who had completed junior high school （36. 19% ） education, lived in rural areas （38. 10% ）, new rural endowment insurance （52.38%）. Some patients had digestive system cancer （56. 19% ） and eastern cooperative oncology group（ECOG） grade score one （94. 29% ）. The average score of CFS was （21.24 ±7.76）. The dimensions of CFS had a negative correlation with FACT-G （all P 〈 0. 05 ）. Multivariate linear regression analysis showed that the three dimensions of CFS had significant effects on quality of life in cancer patients with chemotherapy （ all P 〈 0. 05 ）. Conclusions The inciednce of cancer-related fatigue are high in cancer patients with chemotherapy. Cancer-related fatigue affects quality of life to considerable degree. Reduction of cancer-related fatigue by health care education can improve cancer patients quality of lite.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2015年第5期462-465,共4页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金(81101750)
关键词
抗肿瘤联合化疗方案
肿瘤
流行病学研究
Antineoplastic combined chemotherapy protocols
Neoplasms
Epidemiologic studies
