摘要
母婴传播是HBV传播的重要途径,阻断HBV的母婴传播对乙型肝炎的防治具有重大意义。简述了HBV母婴阻断于分娩前、分娩时、分娩后3个阶段的现行方案,总结了各阶段阻断方案中存在的争议,分析了隐匿性感染和乙型肝炎生殖细胞传染在HBV母婴传播中的重要性。提出乙型肝炎母婴阻断现行方案有待进一步完善和改进,乙型肝炎的隐匿性感染和生殖细胞传染仍需要得到重视。
Mother-to-child transmission （MTCT）is an important way of hepatitis B virus （HBV）transmission.Blocking the HBV MTCT has a great significance for the prevention and treatment of hepatitis B.This article reviews the current blocking strategies implemented in the antepar-tum,peripartum,and postpartum stages,and summarizes the controversies existing in the blocking strategies in different stages.The significance of HBV occult infection and germ cell transmission in the HBV MTCT is analyzed.The results indicate that the current strategies for the prevention of hepatitis B MTCT need further improvement.Attentions should be focused on HBV occult infection and germ cell transmission.
出处
《临床肝胆病杂志》
CAS
2015年第4期500-504,共5页
Journal of Clinical Hepatology
基金
国家临床重点专科建设项目(WJWYA-2014-004)
"十二五"艾滋病和病毒性肝炎等重大传染病防治(2012ZX10002001-001)
关键词
肝炎
乙型
疾病传播
垂直
母婴阻断
主被动联合免疫
hepatitis B
disease transmission,vertical
prevention of mother-to-child transmission
active and passive immunization
