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子痫前期患者产后chemerin水平与血压昼夜节律的关系 被引量：3

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摘要 目的探讨子痫前期(PE)患者产后血浆chemerin水平与血压昼夜节律的关系。方法 42例重度PE患者根据产后血压节律分为杓型组(n=11)和非杓型组(n=31),选择同期正常分娩后的妇女20例作为对照组。对患者产后7 d内进行动态血压监测,同时分别用酶联免疫吸附测定法(ELISA)、免疫比浊法和放射免疫法检测产妇血浆中chemerin、C反应蛋白、白细胞介素-6及肿瘤坏死因子-α水平。结果非杓型组和杓型组产后chemerin水平均显著高于对照组(P<0.001,P<0.05);非杓型组chemerin水平的升高较杓型组更为显著。杓型组和非杓型组血浆chemerin水平与收缩压和舒张压均存在显著相关性(P<0.05)。结论 PE孕妇产后血浆chemerin水平与血压昼夜节律具有密切的关系,可作为PE患者产后预测心血管疾病发生的风险因子。
作者 吕莉娟 牛建民 温济英 余凡 雷琼
机构地区 广东省妇幼保健院妇产科
出处 《广东医学》 CAS 北大核心 2015年第7期1073-1075,共3页 Guangdong Medical Journal
关键词 CHEMERIN 动态血压监测 子痫前期
分类号 R363 [医药卫生—病理学]
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参考文献9

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同被引文献34

  • 1黄峻,鞠文东,熊小英,陈昂,吴礼凤.子痫前期孕妇血压昼夜节律异常与围生儿结局的关系分析[J].江苏实用心电学杂志,2013,22(2):576-579. 被引量：8
  • 2郭海荣,芦胜群,刘萍.子痫前期-子痫的病因学研究[J].中国误诊学杂志,2008,8(4):776-778. 被引量：2
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  • 5SAFTLAS A F,TRICHE E W,BEYDOUN H,et al.Does chocolate intake during pregnancy reduce the risks of preeclampsia and gestational hypertension[J].Ann Epidemiol,2010,20(8):584-591.
  • 6HUANG Q T,ZHANG M,ZHONG M,et al.Advanced glycation end products as an upstream molecule triggers ROS-induced s Flt-1 production in extravillous trophoblasts:a novel bridge between oxidative stress and preeclampsia[J].Placenta,2013,34(12):1177-1182.
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  • 8VALDS E,SEPU'LVEDA-MARTNEZ A,MANUKIN B,et al.Assessment of pregestational insulin resistance as a risk factor of preeclampsia[J].Gynecol Obstet Invest,2014,77(2):111-116.
  • 9MIEHLE K,STEPAN H,FASSHAUER M.Leptin,adiponectin and other adipokines in gestational diabetes mellitus and pre-eclampsia[J].Clin Endocrinol(Oxf),2012,76(1):2-11.
  • 10SCIFRES C M,CATOV J M,SIMHAN H.Maternal serum fatty acid binding protein 4(FABP4)and the development of preeclampsia[J].J Clin Endocrinol Metab,2012,97(3):349-356.

二级引证文献11

广东医学
2015年 第7期

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