摘要
目的：观察凯妮汀（克霉唑阴道片）联合定君生（阴道用乳杆菌活菌胶囊）治疗妊娠期外阴阴道假丝酵母菌病（VVC）的临床效果。方法：将60例妊娠期VVC的孕妇分为研究组及对照组。对照组按常规治疗,凯妮汀1片0.5 g,置于阴道深部,睡前使用,单次用药。研究组按常规治疗,凯妮汀1片0.5 g,置于阴道深部,睡前使用,单次用药;第4天再给予定君生1粒置于阴道深部,每晚睡前使用,连续7 d。比较两组治疗前后的阴道清洁度、阴道p H值及治愈率,观察其治疗效果。结果：研究组治疗后阴道清洁度Ⅰ-Ⅱ度占90.00%,治愈率90.00%,对照组治疗后清洁度Ⅰ-Ⅱ度占66.67%,治愈率66.67%,阴道p H值治疗前后比较差异有统计学意义（P〈0.05）。结论：对于妊娠期VVC,在抗真菌治疗基础上加用乳杆菌制剂即凯妮汀联合定君生不失为一种疗效确切的治疗方案,具有临床推广价值。
Objective：To observe clinical effect of canesten clotrimazole vaginal tablet joint born on jun（vagina lactobacillus bacteria live capsule）treating vulva vagina candida disease during pregnancy（VVC）. Method：60 cases of pregnancy VVC pregnant women were divided into research group and the control group. Control group was given routine treatment,canesten 1 piece of 0.5 g,deep into the vagina,use before bedtime,single drug used. Research group was given the conventional treatment,canesten 1 piece of 0.5 g,deep into the vagina,used before bedtime,single drug use. 4 days to give born on jun 1 grain of deep in the vagina,used before sleep every night,7 days in a row. The two groups before and after the treatment of vaginal cleanness,vaginal pH value and the cure rate were compared,the therapeutic effect was observed. Result：The vaginal cleannessⅠ-Ⅱdegrees accounted for 90.00%,the cure rate was 90.00%of research group after the treatment,cleanlinessⅠ-Ⅱdegrees accounted for 66.67%,the cure rate was 66.67%of control group.The vaginal pH value before and after treatment comparison difference was statistically significant（P〈0.05）. Conclusion：For pregnancy VVC,on the basis of antifungal therapy combined with lactobacillus preparation namely canesten joint born on jun can yet be regarded as a kind of curative effect of treatment,clinical popularization value.
出处
《中国医学创新》
CAS
2015年第9期7-10,共4页
Medical Innovation of China
基金
广东省佛山市卫生局医学科研课题(2014267)
