摘要
目的探讨泮托拉唑、吗丁啉及铝碳酸镁咀嚼片联合治疗慢性胃炎的疗效。方法选取2013年1月～2014年1月来我院就诊的慢性胃炎患者82例,分为观察组和对照组,每组各41例,两组患者均予铝碳酸镁咀嚼片1.0g口服,3次/d,吗丁啉10mg餐前30min口服,3次/d,观察组患者同时加用泮托拉唑40mg饭后口服,每天1次,疗程2周,治疗后随访半年。结果治疗后,观察组的总有效率为92.68%,明显高于对照组的有效率,差异具有统计学意义（x^2=4.753,P〈0.05）。治疗后,两组患者的上腹疼痛、上腹不适、腹胀、乏力、嗳气、食欲不振、恶心、呕吐均较治疗前明显减少,且观察组较对照组上述临床表现减少更显著。结论泮托拉唑、吗丁啉及铝碳酸镁咀嚼片联合治疗慢性胃炎具有较好的临床疗效,安全性好。
Objective To investigate the effects of pantoprazole, domperidone combined Hydrotalcite Chewable Tablets in treatment of chronic gastritis. Methods 82 cases of patients with chronic gastritis in our hospital from January 2013 to January 2014, were divided into an observation group and a control group, 41 cases in each group, the two groups received Hydrotalcite Chewable Tablets 1 g orally, 3 times / day, half an hour before meal oral domperidone 10 mg, 3 times/day, the observation group further received pantoprazole 40 mg oral, 1 times/day, for 2 weeks, the two groups were followed up for half a year. Results After treatment, the total effective rate of observation group was 92.68%, significantly higher than that in the control group（x^2=4.753, P〈0.05）. After treatment, the two groups of patients with upper abdominal pain, abdominal discomfort, bloating, fatigue, belch, anorexia, nausea and vomiting were obviously reduced than before, the clinical manifestations of observation group decreased more significantly. Conclusion Pantoprazole, domperidone combined hydrotalcite chewable tablets in the treatment of chronic gastritis has good clinical efficacy and good safety.
出处
《中国医药科学》
2015年第4期57-59,共3页
China Medicine And Pharmacy
关键词
慢性胃炎
泮托拉唑
吗丁啉
铝碳酸镁咀嚼片
Chronic gastritis
Pantoprazole
Domperidone
Hydrotalcite chewable tablets
