摘要
目的：探讨高龄子宫内膜癌患者的预后。方法选取经病理检查确诊为子宫内膜癌的高龄患者108例，根据病理临床分期确定手术类型并对所有患者进行2～84个月随访，描绘患者的总体生存曲线，采用单因素和多因素分析患者预后的影响因素。结果108例高龄子宫内膜癌患者总体3年生存率为86．1％，总体5年生存率为74．1％。单因素分析发现，肌层浸润深度、病理组织学分级、组织学类型、淋巴结转移，χ2趋势检验差异均有统计学意义（P＜0．05）。多因素分析发现，肌层浸润深度（ OR＝1．828，95％CI＝1．054～3．170）、病理组织学分级（ OR＝3．264，95％CI＝1．574～6．767）、组织学类型（OR＝2．282，95％CI＝1．226～4．247）、淋巴结转移（OR＝1．696，95％CI＝1．152～2．495）是高龄子宫内膜癌患者预后差的危险因素。结论肌层浸润深、子宫内膜癌分化程度低、非子宫内膜腺癌、有淋巴结转移的高龄子宫内膜癌患者预后差。
Objective To explore the prognosis of elderly patients with endometrial carcinoma .Methods 108 elderly patients confirmed by pathological examination to be endometrial carcinoma were selected and was conducted followed up for 2-84 months.Survival curve was drawn and prognosis was studied by single factor analysis combined with multivariate analysis .Re-sults The 3-year and 5-year overall survival rates of 108 elderly patients with endometrial carcinoma were 86.1%and 74.1%. Single factor analysis revealed that depth of myometrial invasion ,histopathologic grading ,histological types ,lymphatic metastasis ,χ2 test for trend difference had statistical significance （P〈0.05）;multivariate analysis showed that depth of myometrial invasion （OR=1.828,95%CI=1.054~3.170）,histopathologic grading（OR=3.264,95%CI=1.574~6.767）,histological types（OR=3.264,95%CI=1.574~6.767）,lymphatic metastasis（OR=1.696,95%CI=1.152~2.495） were risk factors for prognosis of patients with edometrial carcinoma .Conclusion Elderly edometrial carcinoma patients with deep myometrial invasion ,low de-gree of differentiation ,non endometrioid adenocarcinoma ,lymph node metastasis has bad prognosis .
出处
《实用癌症杂志》
2014年第4期423-425,428,共4页
The Practical Journal of Cancer
关键词
子宫内膜癌
预后
影响因素
Edometrial carcinoma
Prognosis
Influencing factors
