摘要
目的:探讨自然周期与促排卵周期对宫腔内人工授精(IUI)治疗结局的影响,以提高IUI治疗的临床效果。方法:收集384个IUI治疗周期,分别采用自然周期、氯米芬、氯米芬+尿促性腺激素、来曲唑、来曲唑+尿促性腺激素、尿促性腺激素治疗,比较自然周期组与促排卵组、不同促排卵方案组之间治疗效果的差异。结果:自然周期组妊娠率为9.33%,促排卵周期组妊娠率为13.27%,促排卵组的妊娠率高于自然周期组,差异有显著性(P<0.05),而促排卵组之间的妊娠率差异无显著性(P>0.05)。结论:促排卵药物的使用是影响人工受精妊娠率的重要因素之一,不同促排卵方案之间IUI治疗结局无差异。
Objective To explore the impacts of natural ovulation cycles and stimulation cycles on the outcome of intrauterine insemination（IUI） in order to improve the clinical effects of IUI. Methods 176 women received 384 stimulation cycles. According to different ovulation stimulation protocols, the women were divided into six groups including natural cycle（NC） group, clomiphene citrate（CC） group, letrozole（LE） group;human menopausal gonadotrophin（HMG） group, CC ＋ HMG group, and LE ＋ HMG group. The pregnancy rate between nature cycles and ovarian hyperstimulation cycles was compared. Results The pregnancy rate was 9.33%in the nature cycle group and 13.27% in the stimulation cycle group, with a significant difference（P〈0.05）;and it dif not differ significantly among the stimulation cycle groups（P〉0.05）. Conclusions Use of ovulationinduction medications is one of the important factors affecting the pregnancy rate of intrauterine insemination.There are no differences in the outcome of IUI among different ovulation stimulation protocols.
出处
《实用医学杂志》
CAS
北大核心
2015年第6期933-936,共4页
The Journal of Practical Medicine
关键词
人工授精
妊娠率
自然周期
促排卵周期
Intrauterine insemination
Pregnancy rate
Natural ovulation cycle
Stimulation cycle
