摘要
目的:了解复旦大学附属上海市第五人民医院世博家园门诊部(以下简称"我院")抗菌药物的限定日费用(DDC),为临床合理用药提供参考。方法:统计2010—2012年我院西药库出库记录,提取不同厂家、不同品种及不同剂型抗菌药物相关信息,采用限定日剂量法,对抗菌药物的DDC进行排序、分析。结果:3年中共用9大类抗菌药物,其中,大环内酯类药的DDC在2011年为最高(64.81元),硝基咪唑类药在2012年为最低(0.09元)。头孢菌素类药中,DDC最高的是注射用盐酸头孢替安(120.84元),最低的是头孢拉定分散片(2.41元),第1代头孢菌素各品种的DDC均未超过9.00元。大环内酯类药中,阿奇霉素干混悬剂与注射用乳糖酸阿奇霉素的DDC逐年下降,且在2012年大环内酯类药仅有1个注射与2个口服品种。氟喹诺酮类药注射与口服剂型的DDC均低于大环内酯类药,其中,2012年盐酸左氧氟沙星氯化钠注射液的DDC为21.25元,盐酸左氧氟沙星片为1.90元,诺氟沙星片为0.77元。结论:2010—2012年,我院大多数抗菌药物的DDC均呈下降趋势,但同一品种不同剂型、剂量或不同厂家的DDC存在差异。
OBJECTIVE：To analyze the defined daily cost （ DDC ） of antibiotics in Expo Home Outpatient Department of Shanghai Fifth People＆#’s Hospital Affiliated to Hehai University （ hereinafter referred to as “our hospital”） so as to provide references for clinical rational use of drug .METHODS：The consumption data of antibiotics from different manufacturers , in different species and different dosage forms from 2010 to 2012 were analyzed using the method of defined daily dose （DDD） and defined daily cost （DDC）.RESULTS： Nine categories of antibiotics were used over the three years .In terms of DDC, macrolide drugs took the lead in 2011（64.81 Yuan） and imidazole nitrate drugs ranked the last in 2012（0.09 Yuan）.Among the cephalosporins used , cefotiam hydrochloride injection took the lead in DDC （ 120.84 Yuan ） and cefradine tablets ranked the last place （ 2.41 Yuan ）; the DDC of all the first-generation cephalosporins were not beyond 9.00 Yuan.Among macrolide drugs , azithromycin dry suspension and injectable azithromycin lactobionate decreased year by year in DDC .In 2012, there only one injection and two oral dosage forms of macrolide drugs available .The DDC of the injection and oral dosage forms of quinolones were lower than that of macrolides . In 2012 , the DDC of levofloxacin sodium chloride injection , levofloxacin tablets and norfloxacin tablets stood at 21.25 Yuan, 1.90 Yuan and 0.77 Yuan, respectively.CONCLUSIONS： From 2010 to 2012 , the DDC of the majority of antimicrobial agents in our hospital assumed declining trend , but the DDC of the same type of drug varied greatly with the difference in dosage forms , doses and manufacturers .
出处
《中国医院用药评价与分析》
2015年第1期87-91,共5页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
抗菌药物
限定日剂量
限定日费用
Antibiotics
Defined daily dose
Defined daily cost
