摘要
目的探讨血浆凝血酶-抗凝血酶复合物(TAT)、D-二聚体(D-D)检测在冠心病早期诊断中的价值。方法选择我院收治的113例冠心病早期患者为观察组,同期在我院健康体检人员127例为对照组;对比2组间血浆D-D、TAT、血脂水平以及凝血指标的差异。结果与对照组比较,观察组血浆D-D、TAT水平显著升高,差异具有统计学意义(P<0.01);观察组总胆固醇、低密度脂蛋白胆固醇、三酰甘油水平均显著高于对照组,观察组高密度脂蛋白胆固醇水平显著低于对照组,2组间差异具有统计学意义(P<0.01);观察组凝血酶原时间和活化部分凝血活酶时间显著低于对照组(P<0.01)。结论血浆D-D、TAT水平、血脂水平以及凝血指标检测有助于冠心病早期诊断,值得临床推广应用。
Objective To explore the value of thrombin-antithrombin complexes（ TAT）,D-dimer（ D-D） in the early diagnosis for coronary artery disease. Methods 113 cases of coronary heart disease in our hospital were chosen as the observation group,and 127 healthy person at the same period were enrolled as control group. The levels of D-D,plasma TAT,blood lipids,blood coagulation index in two groups were detected and compared. Results The plasma levels of DD,TAT in the observation group were significantly higher than those in the control group（ P〈0. 01）. The levels of total cholesterol,low density lipoprotein,three triglyceride in the observation group were significantly higher than those in the control group,and the level of high density lipoprotein was lower than that of the control group（ P〈0. 01）. The prothrombin time and activated partial thromboplastin time in the observation group were significantly lower than those in the control group（ P〈0. 01）. Conclusions Plasma D-D,TAT levels,blood lipid and blood coagulation index might be helpful for early diagnosis of coronary heart disease.
出处
《实用老年医学》
CAS
2015年第2期131-133,共3页
Practical Geriatrics
