摘要
目的:研究狭叶獐牙菜的主要化学成分。方法:采用硅胶柱层析分离纯化化合物,依据理化性质和现代波谱技术进行结构鉴定。结果 :从氯仿部位分离鉴定了4个单体化合物,分别为:齐墩果酸(1)、乌苏酸(2)、羽扇豆醇(3)、3β-羟基-11α,12α-环氧齐敦果-28,13β-内酯(4)。结论:除化合物(1)外,化合物(2)、(3)、(4)为首次从该药用植物中分离得到。
Objective： To explore the chemical constituents of Swertia angustifolia Buch. Methods： Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral analysis. Results： Four monomeric compounds were obtained from trichloromethane extract of S. angustifolia and were identified as asoleanolic acid（1）, ursolic acid（2）, lupeol（3）, and 3β- hydroxy- 11α,12α- epoxyoleanan- 28,13β- olide（4）.Conclusion： Compounds（2）,（3）and（4）were obtained from S. angustifolia for the first time.
基金
国家自然科学基金资助项目(81260677)
云南省教育厅基金资助项目(2012Z118)
关键词
狭叶獐牙菜
化学成分
萜类化合物
Swertia angustifolia Buch.
chemical constituents
terpenoids
