摘要
目的探讨烟雾病患者后交通动脉(PCo A)开放与否,对颅外段颈内动脉(EICA)血流动力学的影响。方法纳入2008年8月至2014年4月,经颅多普勒超声(TCD)与颈动脉彩色多普勒血流显像(CDFI)联合检测并经DSA证实的烟雾病患者单侧病变103例。根据DSA显示PCo A开放情况,将患者分为PCo A未开放组(83例),PCo A开放组(20例);选择同期接受TCD和CDFI筛查的健康者80名作为对照组。通过CDFI及TCD分别检测两组对象EICA及大脑后动脉(PCA)的收缩期峰值流速(PSV)、舒张期末流速(EDV)、血管阻力指数(RI)和(或)血管搏动指数(PI)。结果 (1)3组PSV、EDV、RI比较,差异有统计学意义(F值分别为5.76、12.24、8.10,均P<0.05)。PCo A未开放组患者病变侧血管EICA的PSV[(42±15)cm/s]、EDV[(14±7)cm/s]均低于对照组[(92±24)、(38±11)cm/s],差异均有统计学意义(均P<0.05);PCo A开放组患者病变侧EICA的PSV低于对照组(P<0.05),但EDV高于对照组(P<0.05)。(2)与对照组比较,PCo A未开放组RI值增高(P<0.01),PCo A开放组RI值降低(P<0.01)。(3)烟雾病组PCA的PSV、EDV高于对照组(P<0.05),PI值低于对照组(P<0.01)。结论烟雾病患者PCo A开放与否,对EICA血流动力学的参数影响不同。PCo A未开放患者的PSV、EDV低于健康者,RI值增高;PCo A开放患者EICA较对照组PSV、RI减低,EDV增高。
Objective Toinvestigatetheeffectofwhetherposteriorcommunicatingartery（PCoA） patent or not on hemodynamics of extracranial internal carotid artery （EICA）in patients with moyamoya disease.Methods Atotalof103consecutivepatientswithmoyamoyadisease（unilaterallesion） detected by transcranial color Doppler ultrasonography （TCD）and Color Doppler flow imagining （CDFI）, and confirmed by digital subtraction angiography （DSA）from August 2008 to April 2014 were enrolled. According to the patency of PCoA showed by DSA,the patients were divided into either a PCoA non-patent group （n=83）and a PCoA patent group （n=20）. Eighty healthy subjects screened by TCD and CDFI in the same period were used as a control group. CDFI and TCD were used to detect the peak systolic velocity （PSV）,end diastolic velocity （EDV）,vascular resistance index （RI）and/or pulsatility index （PI）of EICA,and posterior cerebral artery （PCA）in subjects of both groups. Results （1 ）There were significant differences in PSV,EDV and RI among the three groups （F=5. 76,12. 24,and 8. 10,respectively;all P〈0. 05）. The PSV of vascular EICA （42 ± 15 cm/s）and EDV （14 ± 7 cm/s）on the lesion sites in patients of the PCoA non-patent group were all lower than those in the control group （92 ± 24 and 38 ± 11 cm/s）. The differences were statistically significant （all P〈0. 05）. The PSV of vascular EICA on the lesion sites＆amp;nbsp;in patients of the PCoA patent group was lower than that of the control group （P〈0. 05）,but EDV was higher than the control group （P〈0. 05）. （2）Compared with the control group,the RI value was increased in the PCoA non-patent group （P〈0. 01）and that was decreased in the PCoA patent group （P〈0. 01）. （3）PSV and EDV of PCA in the moyamoya disease group were higher than those of the control group （P〈0.05）,andthePIvaluewaslowerthanthatofthecontrolgroup（P〈0.01）.Conclusion Whether PCoA patent or not in patients with moyamoya disease have different influences on hemodynamic parameters of EICA. PSV and EDV of the patients with PCoA non-patent are lower than those of the healthy subjects and their RI values are increased. EICA of the patent group is lower than PSV and RI of the control group, and their EDV is increased.
出处
《中国脑血管病杂志》
CAS
CSCD
北大核心
2015年第1期27-31,共5页
Chinese Journal of Cerebrovascular Diseases
关键词
脑底血管网病
后交通动脉
大脑后动脉
血流动力学
超声检查
Moyamoyadisease
Posteriorcommunicatingartery
Posteriorcerebralartery
Hemodynamics
Ultrasonography
