摘要
目的探讨全麻复合硬膜外阻滞麻醉在老年结直肠癌患者腹腔镜手术中的应用,以期为临床提供参考。方法选取2013年1月至2014年1月间接受治疗的80例结直肠癌患者,采用随机数字表法分成观察组和对照组,每组40例。观察组患者采用全麻复合硬膜外阻滞麻醉方式,对照组采用全麻方式,观察患者心率(HR)及平均动脉压(MAP)变化。结果两组患者经过麻醉后,其HR显著升高,麻醉后与麻醉前、手术结束放气后5 min相比,差异均有统计学意义(均P<0.05);麻醉后与气腹前后的10 min的HR相比,差异均有统计学意义(均P<0.05)。两组患者经过麻醉后,其MAP显著升高,麻醉后与麻醉前、手术结束放气后5 min相比,差异均有统计学意义(均P<0.05);麻醉后与气腹前后的10 min的MAP相比,差异有统计学意义(t=6.973、5.573,P<0.05)。观察组患者镇痛肌松效果为优38例(95.0%),良2例(5.0%),与对照组差异有统计学意义(P<0.05)。结论全麻复合硬膜外阻滞麻醉用于老年结直肠癌腹腔镜手术,效果显著,具有干扰小、应激反应轻、并发症少等特点,是一种值得应用的麻醉方式。
Objective To investigate the efficacy of general anesthesia combined with epidural anesthesia for elderly patients with colorectal cancer in laparoscopic surgery. Methods Between January 2013 and January 2014,eighty cases of patients with colorectal cancer were chosen in the Fourth Hospital Affiliated to China Medical University and were randomly divided into two groups： the observation group and the control group,with 40 patients in each group respectively. Patients in the observation group were treated with general anesthesia combined with epidural anesthesia and patients in the control group accepted general anesthesia. The heart rate（ HR） and mean arterial pressure（ MAP） were compared. Results After the two groups were anesthetized,the HR was significantly increased,and before anesthesia,after the end of surgery compared with 5 min deflated,the difference was not statistically significant（ t = 1. 084,0. 921,P〈0. 05）,for around 10 min of pneumoperitoneum HR,the difference was statistically significant（ t = 6. 973,5. 573,P〈0. 05）. After anesthesia for patients in the two groups,the MAP was significantly elevated,and before anesthesia,surgery deflated after the end of 5min contrast,the difference was not statistically significant（ t = 1. 231,1. 281,P〈0. 05）,for around 10 min of pneumoperitoneum after MAP contrast,the difference was statistically significant（ t = 6. 973,5. 573,P〈0. 05）. Patients in the observation group were 38 patients excellent cases（ 95. 0%）,2 good cases（ 5. 0%）,0 poor cases（ 0. 0%）. Compared with the control group,the difference was statistically significant（ P〈0. 05）. Conclusions The efficacy of general anesthesia combined with epidural anesthesia for laparoscopic surgery in elderly with colorectal cancer is significant,with small interfering light stress response,fewer complications and other characteristics,and is worthy application of anesthesia.
出处
《中国肿瘤临床与康复》
2015年第2期191-193,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
基金
浙江省卫生厅基金项目
No.2012KYB032
关键词
全麻复合硬膜外阻滞麻醉
结直肠癌
腹腔镜手术
Anesthesia combined with epidural anesthesia
Colorectal neoplasms
Laparoscopic surgery
