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Rotational effect in two-dimensional cooperative directed transport 被引量:1

Rotational effect in two-dimensional cooperative directed transport
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摘要 In this review we investigate the rotation effect in the motion of coupled dimer in a two-dimensional asymmetric periodic potential. Free rotation does not generate directed transport in translational direction, while we find it plays an critical role in the motors motility when the dimer moves under the effect of asymmetry ratchet potential. In the presence of external force, we study the relation between the average current and the force numerically and theoretically. The numerical results show that only appropriate driving force could produce nonzero current and there are current transitions when the force is large enough. An analysis of stability analysis of limit cycles is applied to explain the occurrence of these transitions. Moreover, we numerically simulate the transport of this coupled dimer driven by the random fluctuations in the rotational direction. The existence of noise smooths the current transitions induced by the driving force and the resonance-like peaks which depend on the rod length emerge in small noise strength. Thanks to the noise in the rotational direction, autonomous motion emerges without the external force and large noise could make the current reversal happen. Eventually, the new mechanism to generate directed transport by the rotation is studied. In this review we investigate the rotation effect in the motion of coupled dimer in a two-dimensional asymmetric periodic potential. Free rotation does not generate directed transport in translational direction, while we find it plays an critical role in the motors motility when the dimer moves under the effect of asymmetry ratchet potential. In the presence of external force, we study the relation between the average current and the force numerically and theoretically. The numerical results show that only appropriate driving force could produce nonzero current and there are current transitions when the force is large enough. An analysis of stability analysis of limit cycles is applied to explain the occurrence of these transitions. Moreover, we numerically simulate the transport of this coupled dimer driven by the random fluctuations in the rotational direction. The existence of noise smooths the current transitions induced by the driving force and the resonance-like peaks which depend on the rod length emerge in small noise strength. Thanks to the noise in the rotational direction, autonomous motion emerges without the external force and large noise could make the current reversal happen. Eventually, the new mechanism to generate directed transport by the rotation is studied.
出处 《Frontiers of physics》 SCIE CSCD 2015年第1期87-94,共8页 物理学前沿(英文版)
基金 We thank Peter Hanggi for valuable dis- cussions. This work has been financially supported by grants from the National Natural Science Foundation of China (Grant No. 11075016) and the Foundation for Doctoral Training from Min- istry of Education (Grant No. 20100003110007).
关键词 molecular motor rotational effect noise rotation-translation coupling directedtranslational motion molecular motor, rotational effect, noise, rotation-translation coupling, directedtranslational motion
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  • 1A. Yildiz, J. N. Forkey, S. A. McKinney, T. Ha, Y. E. Gold- man, and P. R. Selvin, Myosin V walks hand-over-hand: Sin- gle fluorophore imaging with 1.5-nm localization, Science, 2003, 300(5628): 2061.
  • 2A. Yildiz, H. Park, D. Safer, Z. Yang, L. Q. Chen, P. R. Selvin, and H. L. Sweeney, Myosin VI steps via a hand- over-hand mechanism with its lever arm undergoing fluctua- tions when attached to actin, J. Biol. Chem., 2004, 279(36): 37223.
  • 3A. Yildiz, M. Tomishige, R. D. Vale, and P. R. Selvin, Ki- nesin walks hand-over-hand, Science, 2004, 303(5658): 676.
  • 4S. L. Reck-Peterson, A. Yildiz, A. P. Carter, A. Gennerich, N. Zhang, and R. D. Vale, Single-molecule analysis of Dyneinprocessivity and stepping behavior, Cell, 2006, 126(2): 335.
  • 5M. yon Delius and D. A. Leigh, Walking molecules, Chem. Soc. Rev., 2011, 40(7): 3656.
  • 6K. Shiroguchi and K. Kinosita, Myosin V walks by lever ac- tion and brownian motion, Science, 2007, 316(5828): 1208.
  • 7A. R. Dunn and J. A. Spudich, Dynamics of the unbound head during myosin V processive translocation, Nat. Struct. Mol. Biol., 2007, 14(3): 246.
  • 8F. Jiilicher, A. Ajdari, and J. Prost, Modeling molecular motors, Rev. Mod. Phys., 1997, 69(4): 1269.
  • 9R. D. Astumian, Thermodynamics and kinetics of a Brown- ian motor, Science, 1997, 276(5314): 917.
  • 10M. Dittrich, J. Yu, and K. Schulten, PcrA Helicase, a molec- ular motor studied from the electronic to the functional level, in: Atomistic Approaches in Modern Biology, edited by M. Reiher, Springer, 2007, pp. 319-347.

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