摘要
黄体是甾体激素的主要来源,正常的黄体功能是维持妊娠所必需。黄体功能不全会导致正常妊娠难以维持。黄体支持及补充适应症包括辅助生殖(ART)助孕后、复发性流产、先兆流产及先兆早产等。目前黄体支持药物包括:黄体酮类、h CG、雌激素及Gn RH-a。常用给药途径包括肌肉注射、经阴道及口服给药等。通过结合近年来国内、外相关领域研究进展及临床应用,对ART中黄体支持的用药选择、孕激素治疗在先兆流产、复发性流产及早产预防中的应用达成部分专家共识,以指导规范的临床应用。
The human corpus luteum is the main source of steroid hormones. Normal luteal function is essential for the maintenance of pregnancy. Luteal phase defect will make it difficult to maintain normal pregnancy. Luteal phase support and supplementation indications include assisted reproduction technology （ART） treatment, recurrent miscarriage, threatened abortion and threatened premature labor, etc. Current luteal support drugs include progesterone, hCG, estrogen and GnRH-a. Common routes of administration involve intramuscular, vaginal and oral, etc. Combined with domestic and foreign research progress and clinical application in recent years, a consensus was reached by part experts to guide the clinical applications on drug selection of ART luteal phase support, progesterone therapy in threatened abortion, recurrent miscarriage and the prevention of preterm.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2015年第1期1-8,共8页
Reproduction and Contraception
