摘要
目的了解宁夏男男性行为者的艾滋病病毒新发感染情况，并分析其影响因素及队列保持情况，为决策提供建议。方法采用前瞻性开放性队列研究方法，2011年4—6月建立队列，6个月及12个月后分别随访。问卷调查收集社会人口学、行为学等信息和艾滋病病毒检测情况。艾滋病新发感染率的影响因素采用COX回归分析。结果剔除本底招募中的18例艾滋病病毒抗体阳性，共调查符合条件的男男性行为者726例。随访组309例中，艾滋病病毒新发感染率为2．90／100人年（95％CI：1．45～5．80）。多因素分析艾滋病病毒新发感染的危险因素为近6个月4个以上性伴（HR=13．82，95％CI：6．55～24．10），保护因素为近1年接受过咨询检测（HR=0．04，95％CI：0．01～0．15）。肛交时使用安全套，接受艾滋病相关服务随访者较脱失者高。脱失人群未婚或离异的比例较高（P〈0．05）。结论宁夏男男性行为人群中HIV发病率较发达地区低，存在不安全性行为，随访人群接受干预的比例较脱失人群高。应加大检测咨询为主的综合干预措施，遏制艾滋病在该人群的传播。
Objective To investigate the HIV infection situation among men who have sex with men（MSM） in Ningxia and to examine the related factors with the HIV infection and the cohort retention. Methods A prospective cohort established during April 2011-June 2011,6 months and 12 months follow-up, patricians completed the questionnaire which included social demographic characteristics, sex behaviors, and other in formations, the influence factors of new HIV infections by COX regression analysis. Results The 726 MSM participants ,310 participants were followed at least two times,the incidence of HIV were 2.90/100 man-year （95% CI： 1.45 ～ 5.80）. The multivariate analysis showed that the more than 4 sexual partners was a risk factors （ HR = 13. 819,95% CI： 6. 547 - 24. 987 ）, and received testing consultation was protective factors （ HR = 0. 040, 95% CI：0. 013 -0. 148 ）. There was statistical difference in condom use with homosexual behavior, acceptability of AIDS related services,and marriage between follow-up group and depigmentation group（P 〈 0.05 ）. Conclusion The HIV incidence of MSM in Ningxia are lower in the developed area, MSM has a certain proportion of unsafe sex behavior, follow-up group acceptability of AIDS related services is higher than depig- mentation group. We should increase the testing and counseling intervention based measures to curb the spread of AIDS in MSM.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2015年第1期50-52,共3页
The Chinese Journal of Dermatovenereology
基金
中美艾滋病防治合作项目(2011-2012-宁夏-10)~~
