期刊文献+

门控心肌灌注断层显像评价扩张型心肌病患者左室同步性的价值

The value of gated myocardial perfusion SPECT in evaluating the left ventricular synchrony of patients with dilated cardiomyopathy
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摘要 目的:本研究主要探讨门控心肌灌注显像诊断扩张型心肌病患者左心室收缩不同步的价值。方法选取在本院接受核素心肌灌注显像的扩心病患者共47例,根据心电图Q RS波时限分为Q RS波正常组(20例)和Q RS波增宽组(27例);选取同时期35例正常受检者作为正常对照组。入选对象行99m Tc‐MIBI心肌灌注显像,观察门控数据,计算不同步指数(AI)以及左室射血分数(EF)、舒张末容积(EDV )、收缩末容积(ESV )等。运用方差分析比较各组间指标,运用秩和检验AI差异,以 P<0.05作为差异具有统计学意义。结果三组EF之间均存在显著差异( P<0.001);QRS增宽组13例为间隔‐侧壁收缩延迟,7例为前壁‐后壁收缩延迟,A I在2~5之间,Q RS波正常组中有2例存在间隔‐侧壁收缩延迟,AI分别为2、3,两组AI差异具有统计学意义( P =0.03)。结论该方法能够直观了解左心室各壁运动的协调性,判断左室收缩延迟的具体部位和延迟程度,对左室不同步的诊断和治疗具有一定价值。 Objective Our study focused on gated myocardial perfusion imaging in the diagnosis of patients with left ven‐tricular dyssynchrony .Methods 47 cases with DCM underwent gated myocardial perfusion imaging ware enrolled .All ca‐ses were grouped according to the duration of QRS :QRS normal group and QRS duration extend group .35 cases of nor‐mal subjects in the same period were taken as normal control group .99m Tc‐MIBI myocardial perfusion imaging was conduc‐ted .AI were calculated ,and EF ,EDV and ESV was recorded .Each group was compared using ANOVA .P〈0 .05 was used as a statistically significant difference .Results There were significant differences of EF ( P〈0 .001) .QRS duration extened group :septum‐lateral contraction delays were observed in 13 cases ,and anterior‐posterior delays in 7 cases .AI was between 2 to 5 .QRS duration normal group :Interval‐septal contraction delays were observed in 2 cases ,AI were 2 , 3 respectively .AI difference between the two groups was statistically significant .Conclusion The method could observe and locate the coordination of left ventricular contraction intuitively ,and could be helpful in the diagnosis and treatment of ventricular dyssynchrony .
出处 《医学影像学杂志》 2014年第12期2102-2105,2124,共5页 Journal of Medical Imaging
基金 江苏省无锡市科技局科技支撑计划(社会发展)(编号:CSE01N1214)
关键词 门控心肌灌注显像 体层摄影术 发射型计算机 单光子 心肌病 扩张型 左室不同步 心脏再同步治疗 Gated myocardial perfusion imaging tomography Emission-computed Single-photon Cardiomyopathy dilated Left ventricular dyssynchrony Cardiac resynchronization therapy
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参考文献15

  • 1黄佳,周青,谢斌,胡波,邓倾,郭瑞强.二维斑点追踪应变成像对冠心病患者左心室同步性的定量研究[J].中华超声影像学杂志,2012,21(6):470-473. 被引量:7
  • 2Matsumoto K, Tanaka H, Miyoshi T, et al. Dynamic left ventricular dyssynchrony assessed on 3-dimensional speckle tracking area strain during dobutamine stress has a negative impact on cardiovascular events in patients with idiopathic di lated cardiomyopathy [J]. Circ J, 2013, 77(7) : 1750-1759.
  • 3Richardson P, MeKenna W, Bristow M, et al. Report of the 1995 world organization/International society and federation of cardiology task force on the definition and classification of cardiomyopathies [J]. Circulation, 1995, 93(5): 841-842.
  • 4黄纲,石洪成.心脏核医学[M].上海:上海科学技术出版社,2011.26-27,79-81.
  • 5Anzouan-Kacou JB, Ncho-Mottoh MP, Konin C, et al. Prev- alence of cardiac dyssynchrony and correlation with atrio-ven- tricular block and QRS width in dilated cardiomyopathy: an echocardiographic study [J]. Cardiovasc J Aft, 2012,23(7) 385-388.
  • 6Anand IS, Carson P, Galle E, et al. Cardiac resynchroniza tion therapy reduces the risk of hospitalization in patients with advanced heart failure: results from the Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure (COMPANION) Trial EJ]- Circulation, 2009, 119: 969- 977.
  • 7Khan FZ, Virdee MS, Palmer CR, et al. Targeted left ven tricular lead placement to guide cardiac resynchronization therapy: the TARGET study: a randomized, controlled trial [J]. J Am Coll Cardiol, 2012, 59(17) : 1509-1518.
  • 8Sogaard P, Egeblad H, Pedersen AK, et al. Sequential ver- sus simultaneous biventrieular resynehronization for severe heart failure: evaluation by tissue Doppler imaging [J]. Cir- culation, 2002, 106: 2078.
  • 9Arsalone G, Giannantomi P, Ricci R, et al. Biventricular pa cing in heart failure: back to basics in the pathophysiology of left nundle block to reduce the number of nonresponders [J]. Am J Cardiol, 2003, 91(94): 55-61.
  • 10李殿富,袁冬兰,曹克将,黄峻,陈季.门控心肌灌注SPECT相位分析技术评价心力衰竭患者左室不同步的价值[J].国际放射医学核医学杂志,2010,34(1):38-41. 被引量:1

二级参考文献21

  • 1Hunt SA,Abraham WT,Chin MH,et al.ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure).J Am Coll Cardiol,2005,46 (6):ele82.
  • 2Bax JJ,Bleeker GB,Marwick TH,et al.Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy.J Am Coll Cardiol,2004,44 (9):1834-1840.
  • 3Chung ES,Leon AR,Tavazzi L,et al.Results of the Predictors of Response to CRT (PROSPECT) trial.Circulation,2008,117 (20):2608-2616.
  • 4Nichols KJ,Bacharach SL,Bergmann SR,et al.ASNC imaging guidelines for nuclear cardiology procedures:Instrumentation quality assurance and performance.J Nucl Cardiol,2007,14(6):e61-e78.
  • 5Chen J,Garcia EV,Folks RD,et al.Onset of left ventricular mechanical contraction as determined by phase analysis of ECGgated myocardial perfusion SPECT imaging:development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony.J Nucl Cardiol,2005,12(6):687-695.
  • 6Bleeker GB,Kaandorp TA,Lamb HJ,et al.Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy.Circulation,2006,113 (7):969-976.
  • 7Garcia EV,Faber TL,Cooke CD,et al.The increasing role of quantification in clinical nuclear cardiology:the Emory approach.J Nucl Cardiol,2007,14(4):420-432.
  • 8Cooke CD,Garcia EV,Cullom SJ,et al.Determining the accuracy of calculating systolic wall thickening using a fast Fourier transform approximation:a simulation study based on canine and patient data.J Nucl Med,1994,35(7):1185-1192.
  • 9Trimble MA,Velazquez EJ,Adams GL,et al.Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony.Nucl Med Commun,2008,29(4):374-381.
  • 10Chen J,Faber TL,Cooke CD,et al.Temporal resolution of multiharmonic phase analysis of ECG-gated myocardial perfusion SPECT studies.J Nucl Cardiol,2008,15(3):383-391.

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