摘要
目的研究泵注与静滴奥曲肽两种不同给药方式治疗急性胰腺炎的临床效果。方法选取2012年1月-2013年12月广东省第二人民医院收治的急性胰腺炎患者77例为研究对象,根据给药方式的不同分为对照组与观察组。对照组给予输液泵静脉滴注奥曲肽治疗,观察组给予泵注奥曲肽治疗,观察两组患者的治疗效果。结果两组患者的治疗效果相比,差异无统计学意义(P>0.05);治疗时间、症状好转时间、血淀粉酶消退时间比较,差异有统计学意义(t=13.6367,P=0.0000;t=6.4275,P=0.0000;t=6.8329,P=0.0000);治疗第3、7天时的C反应蛋白含量比较,差异有统计学意义(t=8.0472,P=0.0000;t=5.9256,P=0.0000)。结论使用微量注射泵泵注奥曲肽治疗急性胰腺炎能更便捷的控制液体输入速度,同时快速改善患者的临床症状,缩短治疗时间,无严重不良反应发生,值得临床推广使用。
Objective To explore clinical efficacy of pumping injection and intravenous dripping of Octreotide in the treatment of patients with acute pancreatitis. Methods Seventy-seven patients with acute pancreatitis were treated as re- search subjects from Jan. 2012 to Dec. 2013 in the Guangdong People＇ s Second Hospital, and divided into the control group and observation group according to different approaches of administrations. Patients in the control group were subjec- ted to the therapy of Octreotide intravenous dripping of infusion pump, and patients in the observation group were subjec- ted to Octreotide pumping injection treatment, and the efficacy between two groups were compared. Results Treatment efficacy between two groups had no significantly different. Comparison of treatment duration, time of improved symptom and time of eliminated blood amylase between two groups were t = 13. 6367 （P = 0. 0000）, t = 6. 4275 （ P = 0. 0000） and t =6. 8329 （P = 0. 0000）, respectively. Comparison in the content of C-reactive protein between two groups were t = 8. 0472 （P = 0. 0000） and t = 5. 9256 （P = 0. 0000） on the third and seventh day. Conclusion The pumping of Octreoti- de injection with micro-injection pump in the treatment of patients with acute panereatitis is capable of controlling the in- fuse speed of liquid in more convenient manner, and improving clinical symptoms of patients and shortening the treatment duration without serious adverse reactions, being worthy of clinical promotion and application.
出处
《胃肠病学和肝病学杂志》
CAS
2014年第12期1468-1470,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
泵注
静滴
奥曲肽
急性胰腺炎
Pumping injection
Intravenous dripping
Octreotide
Acute pancreatitis
