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类风湿性关节炎危险因素的logistic回归分析 被引量:14

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摘要 目的采用配对病例对照研究及logistic回归分析方法,探索风湿性关节炎可能的危险因素,为该病的病因研究及预防提供依据。方法 559例经确诊的类风湿关节炎患者作为病例组,选取同地区性别及年龄相近的健康人1150人作为对照组,采用自行编制的调查问卷,由调查员现场调查、核查后收回。对所有危险因素先单因素分析进行筛选,计量资料两组之间的比较采用配对样本t检验,计数资料的比较采用χ2检验,将P<0.05的因素纳入非条件logistic回归模型进行分析,采用backward conditional法;检验水准α=0.05,P<0.05认为有统计学意义,所有分析均采用SPSS17.0完成。结果风湿性关节炎受多种危险因素影响,家族史、潮湿环境、中重度体力劳动、个人性格、饮食清淡和外伤史为男女共同的危险因素;初潮年龄≥17岁、初次分娩年龄≤21岁为女性特有的危险因素;吸烟和口服避孕药史为女性可能的保护因素。结论风湿性关节炎的发病和多种危险因素有关,女性的危险因素多于男性。
作者 何蛟 贾治林
出处 《中国卫生统计》 CSCD 北大核心 2014年第6期976-978,共3页 Chinese Journal of Health Statistics
基金 大连市科技计划项目(2012E15SF166)
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参考文献13

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