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苏州市14起诺如病毒胃肠炎暴发疫情流行特征分析 被引量:42

Characteristic of 14 norovirus gastroenteritis outbreaks in Suzhou City
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摘要 目的了解苏州市诺如病毒胃肠炎暴发疫情的流行病学特征。方法对2010-2014年发生的14起诺如病毒胃肠炎暴发疫情进行描述性流行病学分析,采用聚合酶链反应对病例肛拭子、粪便、呕吐物、水、环境涂抹标本进行核酸检测。结果 2011-2014年,苏州市共报告14起诺如病毒胃肠炎暴发疫情,罹患率波动范围为0.89%~21.18%。14起疫情中12起(85.71%)发生于托幼机构和中小学校,医院、农村各1起。全年均有发生,但以寒冷季节发生较多。仅1起查明与二次供水受到污染有关,13起未证实暴发原因。核酸检测结果12起由诺如病毒GII基因组引起,2起由GI基因组引起。结论诺如病毒已成为苏州市急性胃肠炎暴发疫情的重要病原,托幼机构和学校是高发场所,GII基因组是主要基因组。在暴发疫情处理中,应加强传染源和传播途径的调查。 Objective To analyze the epidemic characteristics of norovirus gastroenteritis outbreaks in Suzhou City.Methods Descriptive epidemiological analysis of 14 norovirus gastroenteritis outbreaks reported from 2010 to 2014were conducted.Specimens of anal swabs,stool,vomit,water and environment smear in the 14 outbreaks were collected and detected for norovirus nucleic acid using polymerase chain reaction.Results Fourteen norovirus gastroenteritis outbreaks occurred from December 2010 to January 2014 in Suzhou City with attack rates from 0.89%~21.18%.Of which,12(85.71%)outbreaks occurred in Nurseries and schools,1(7.14%)outbreak occurred in hospital and 1(7.14%)outbreak occurred in village.Outbreaks occurred in every season,but with a higher incidence in cold season.Only 1outbreak was identified caused by secondary water contamination.The reasons of other 13 outbreaks had not been identified.By pathogen detection,12 outbreaks were caused by norovirus GII genogroup and 2outbreaks were caused by GI genogroup.Conclusion Norovirus has become an important cause of acute gastroenteritis outbreak in Suzhou City.Nurseries and schools are the important places of norovirus gastroenteritis outbreaks.GII genogroup was the major genogroup which caused the norovirus gastroenteritis outbreaks in Suzhou City.During the outbreak deal,the investigation about source of infection and route of transmission should be strengthened.
出处 《江苏预防医学》 CAS 2014年第6期14-16,共3页 Jiangsu Journal of Preventive Medicine
基金 2013年苏州市饮用水安全与水性疾病监测公共服务平台课题(SZPT2013002)
关键词 诺如病毒 急性胃肠炎 暴发疫情 基因组 norovirus gastroenteritis outbreak genogroup
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