期刊文献+

参麦注射液对维持性血液透析气阴两虚型患者血管内皮功能的影响 被引量:4

Effect of Shenmai Injection on Vascular Endothelial Function in Maintenance Hemodialysis Patients with Deficiency of Qi and Yin
在线阅读 下载PDF
导出
摘要 目的:观察参麦注射液对血液透析气阴两虚型患者血管内皮功能的影响。方法:选择透析中心维持性血液透析患者60例,分为治疗组和对照组,治疗组在常规血透用药的基础上给予参麦注射液,对照组仅给予常规血透用药,治疗6个月,观察治疗前后两组患者的中医证候积分、血红蛋白、血白蛋白以及血ET-1水平的变化。结果:1治疗后,参麦组中医证候实证积分降低(p<0.05),其总体有效率高于对照组;2治疗后,参麦组的ET-1水平较治疗前明显降低(P<0.05)。结论:参麦注射液可以减轻透析患者的血管内皮细胞损伤。 Objective:To investigate the effect of Shenmai injection on endothelial cell function in MHD pa -tients with deficiency of qi and yin syndrome.Methods:60 cases of hemodialysis patients were randomly allocated into two groups:the Shenmai group and the control group ,with 30 cases in each group.TCM syndrome scores and hemoglobin,albumin and ET -1 were determined in all patients before and after treatment.Results:After 6months’treatment,the TCM syndrome scores and ET -1 level in Shenmai group were much lower than those be-fore treatment ( P〈0.05 ).Conclusion:Shenmai injection could effectively reduce the injury of vascular endo-thelial cell.
出处 《中国中医药科技》 CAS 2014年第5期484-485,共2页 Chinese Journal of Traditional Medical Science and Technology
基金 温州市卫生局课题No.2011B034
关键词 参麦注射液 维持性血液透析 气阴两虚型 血管内皮功能 Shenmai injection maintenance hemodialysis(MHD) deficiency of qi and yin vescular endot -helial function
  • 相关文献

参考文献7

  • 1俞锐敏,周羽竝,熊爱华,扬钦河.参麦注射液对大鼠心肌缺血及NO形成的影响[J].广东医学,2004,25(12):1382-1384. 被引量:6
  • 2张雯,陶筱娟,程军,汪卫,王璞,程擎天,羊淑敏.参麦注射液对维持性血液透析患者微炎症状态的影响[J].浙江中西医结合杂志,2008,18(11):684-685. 被引量:5
  • 3Go AS,Chertow GN’Fan D,et al. Chronic kidney disease and therisks of death,cardiovascular events,and hospitalization. N Engl JMed,2004,351:1296.
  • 4Apegianni A,Dovas S,Bantis C,et al. Carotid atherosclerosis andendothelial cell adhesion molecules as predictors of long - termoutcome in chronic hemodialysis oatient Am J Nephrol, 2008,28 :265.
  • 5Longaretti L,Benigini A. Endothelin receptor selectivity in chronicrenal failure. Eur J Clin Invest ,2009,39 ( S2) :32.
  • 6Ohkita M, Takaoka M, Matsumura Y. Drug discovery for overco-ming chronic kidney disease CKD the endothelin ET B receptor/nitric oxide system functions as a protective factor in CKD. J Phar-macol Sci ,2009,109( 1):7.
  • 7Ashimoto H,Kitagawa K,Kuwabara K,et al Circulating adhesionmolecules are correlated with ultrasonic assessment of carotidplaques. Clin Sci(Lond) ,2003,104(5) :521.

二级参考文献12

  • 1钮炜西,华宁,齐帜.心力衰竭患者心功能的改善与参麦注射液及血清炎症因子水平的关系[J].中国临床康复,2005,9(19):134-135. 被引量:26
  • 2Stenvinkel P, Heimburger O, Paultre F, et al. Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int, 1999,55: 1899- 1911
  • 3Kalantar-Zndeh K,Block G, Hmnphreys MH, et al. Reepidemiology of cardiovascular risk fatom in maintensrme dialysis patients. Kidney Int ,2003,63 (3) :793-808
  • 4Stenvinkel P. Inflammatory and atheroselerotic interactions in the depleted uremic patient. Blood Purif, 2001,19 ( 5 ) : 53-61
  • 5Tsirpanlis G, Bagos P, Ioannou D, et al. The variability and accurate assessment of microinflammation in haemodialysis patients. Nephrol Dial Transplant,2004,19( 1 ) : 150-157
  • 6Schindler R. Causes and therapy of microinflammation in renal failure. Nehprol Dial Transplant, 2004,19 (5) : 34-40
  • 7Young LH, Ikeda Y, Lefer AM. Caveolin- 1 peptide exerts cardiopritective effects in myocardial ischemia - reperfusion via nitric oxide mechanism. Am J Physiol Heart Circ Physiol, 2001,280(6): 2489
  • 8Noyoshima H, Nasa Y, Hashizume Y, et al. Modulation of cAMP- mediated vasorelaxation by endothelial nitric oxide and basal cGMP in vascular smooth muscle. J Cardiovasc Pharmacol, 1998, 32:543
  • 9Sumeray MS, Rees DD, Yellon DM. Infarction Size and Nitric Oxide Synthesase in Murine Myocardium. J Mol Cell Cardiol, 2000,32
  • 10汤军,黄琦,徐志瑛,蔡宛如,钱华,宋康.麦冬多糖的免疫活性研究[J].中国中医基础医学杂志,1998,4(9):44-46. 被引量:51

共引文献8

同被引文献57

引证文献4

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部