摘要
本文对苍术多糖的提取、分离纯化工艺、含量测定方法以及药理作用等方面进行系统综述。其中从苍术多糖的提取率可知,采用超声提取法进行提取的效果最好,其次是水提法和碱提法联合使用;纯化苍术多糖时去除蛋白最常用的方法为三氯乙酸法,采用两种方法联用(三氯乙酸-Sevage法)得率更高;苯酚-硫酸法是测量多糖类成分的最常用方法;药理活性包括免疫调节、改善糖代谢紊乱、保护肝脏等作用。
The article systematically reviewed the extraction method, separation method, content determination and pharmacologi- cal effects of Rh/zoma atractylodis polysaccharides. The extraction rate as the index, the ultrasonic extraction method was the best fol- lowed by the water extraction combined with alkali extraction. Triehloroacetic acid precipitation was an effective method commonly used to purify the polysaccharides, while the combination method (ttrichloroacetie acid-Sevage) was more effective. The common content determination method was phenol-sulfuric acid method, and it was also useful in the detection of Rhizoma atractylodis polysaccharides. The pharmacological activities of Rhizoma atractylodis polysaccharides included immune regulation, improving glucose metabolism, pro- tecting liver and so on.
出处
《中国药师》
CAS
2014年第8期1393-1395,共3页
China Pharmacist
基金
湖北医药学院"2011计划"2013年度创新团队项目(编号:2011JH-2013CXTT12)
关键词
苍术多糖
提取分离
含量测定
药理活性
Rhizoma atractylodis polysaccharides
Extraction and separation
Content determination
Pharmacological activity