摘要
目的观察手术治疗儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床疗效,探讨主要致病因素和影响手术疗效的主要原因。方法选取OSAHS患儿85例,进行手术治疗,观察综合疗效,分析治疗前后扁桃体及腺样体肥大程度与呼吸暂停指数(AI)、呼吸紊乱指数(AHI)及最低血氧饱和度(LSaO2)的相关性。结果术后85例患儿治愈率达90.59%,术后AI、AHI、LSaO2的平均值均显著优于术前(P<0.01)。术前AI平均值无显著差异,AHI平均值随着扁桃体肥大程度的增加而升高,LSaO2平均值随着扁桃体肥大程度的增加而下降;术后2个月时AI、AHI及LSaO2均较术前显著改善(P<0.05或P<0.01)。术前腺样体中度组AI及AHI平均值显著低于重度组(P<0.01),LSaO2显著高于重度组(P<0.01);术后2组AI、AHI及LSaO2均较术前显著改善(P<0.01),腺样体中度组各指标仍优于重度组(P<0.01)。结论儿童OSAHS最主要的病因为鼻咽气道狭窄,且病情严重程度与气道狭窄程度密切相关。手术治疗可有效缓解气道狭窄情况,改善通气功能,减轻并消除临床症状。
Objective To observe the clinical efficacy of surgeries on treatment of children with obstructive sleep apnea hypopnea syndrome（ OSAHS） so as to explore the main pathogenic factors and the primary causes influencing surgical efficacy. Methods A total of 85 children with OSAHS were selected and given surgical therapies to observe the comprehensive efficacy and analyze the relevance between hypertrophy degrees of tonsils and adenoids with apnea index（ AI）,apnea hypopnea index（ AHI） and the lowest arterial oxygen saturation（ LSaO2） before and after treatment. Results After operation,the recovery rate of all children was 90. 59%,and the mean values of AI,AHI and LSaO2 were evidently better than treatment before（ P〈 0. 01）. There was no significant difference in AI before treatment while AHI was in positive relation but LSaO2 in negative association with hypertrophy degree of tonsils,and AI,AHI and LSaO2 were improved markedly 2 months after treatment than treatment before（ P〈 0. 05 or P〈 0. 01）. Before operation,adenoid group in degree Ⅱ was obviously lower in AI and AHI but apparently higher in than adenoid group in degree Ⅲ（ P〈 0. 01）; after treatment, AI, AHI and LSaO2 were evidently better than treatment before（ P〈 0. 0 1）,and better in adenoid group in degree Ⅱ than in adenoid group in degree Ⅲ（ P〈 0. 01）. Conclusion The main cause of children with OSAHS is nasopharynx airway stenosis,whose severity is in close association with airway stenosis degree,for which the surgeries can effectively remiss the condition,improve respiratory function and eliminate or even resolve the clinical symptoms.
出处
《实用临床医药杂志》
CAS
2014年第15期59-62,共4页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11321276)
