摘要
目的运用合理用药监测系统(PASS)对医院门诊处方进行监测分析,运用一系列综合干预措施提高合理用药水平。方法从2013年起,医院临床药师运用技术和行政等综合措施干预医生选药、用药,利用PASS分析干预前(2012年)及干预后(2013年)门诊处方28 013张和29 310张,从药物相互作用、给药途径、药物用法用量及儿童用药等方面对问题医嘱进行分析。结果 2012年,门诊不合理用药医嘱为1 693条,2013年仅297条,发生率分别为6.04%和1.01%,差异有统计学意义(P<0.05)。综合干预后,药物相互作用、给药途径、药物用法用量及儿童用药等方面的问题医嘱数量均较干预前显著下降(P<0.05)。结论 PASS系统对医院门诊处方中的不合理用药情况能进行有效监测,综合干预措施能显著提高医院临床合理用药水平,值得医院药房推广。
Objective To monitor and analyze the outpatient prescriptions of our hospital by using the prescription automatic screening system（PASS）, and to apply a series of comprehensive measures to increase the level of reasonable drug use. Methods The clinical pharmacists in our hospital applied a series of comprehensive intervention measures of technique and administration to perform the in-tervention on the doctors＆#39; drug selection and drug use since 2013. PASS was applied to analyze the problematic medical orders in the aspects of the drug interaction, administration route, usage, dosage and child drug use among 28 013 and 29 310 pieces of outpatient prescription before intervention（2012） and after intervention（2013） respectively. Results There were 1 693 irrational medication orders in 2012, while 297 irrational medication orders in 2013, the incidence rates were 6. 04% and 1. 01% respectively, the difference be-tween them had statistical significance（ P ﹤ 0. 05） . The number of the problematic medical orders in the aspects mentioned above after the comprehensive intervention was significantly decreased compared with before intervention（ P ﹤ 0. 05） . Conclusion PASS can effec-tively monitor the irrational drug use in the outpatient prescriptions and the comprehensive intervention measures can significantly in-crease the level of rational drug use in clinic, which is worthy of being promoted in the hospital pharmacy.
出处
《中国药业》
CAS
2014年第15期71-73,共3页
China Pharmaceuticals
基金
辽宁省大连市科学基金项目
项目编号:2012225019
关键词
合理用药监测系统
综合干预
门诊处方
合理用药
prescription automatic screening system
comprehensive intervention
outpatient prescription
rational drug use
