摘要
Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether acti- vation of autophagy increases or decreases the rate of neuronal death is still under debate. This review summarizes the potential role and possible signaling pathway of autophagy in neuronal survival after cerebral ischemia and proposes that autophagy has dual effects.
Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether acti- vation of autophagy increases or decreases the rate of neuronal death is still under debate. This review summarizes the potential role and possible signaling pathway of autophagy in neuronal survival after cerebral ischemia and proposes that autophagy has dual effects.
基金
supported by grants from the project of National Natural Science Foundation of China,No.31171014 and 31371065
the project of Science and Technology Commission of Board of Health of Shanghai,China,No.20134125
the Key Specialty(disease) Declaration of Pudong New Area’s Health System
