摘要
目的：观察支气管哮喘缓解期患者中医药治疗前后的中医四诊信息、证型及肺功能指标的变化，以探讨具有中医特色的疗效评价指标。方法：利用中医舌面象一体仪、中医问诊量表、脉象仪、声诊信息采集系统、肺功能仪采集33例支气管哮喘缓解期患者治疗前后（1~5个月）的四诊信息及肺功能指标，利用单因素方差分析等方法，分析治疗前后四诊参数和肺功能指标的变化规律。结果：哮喘患者经中医药治疗后面色及舌体子区域的颜色、苔色等均有显著变化的参数；哮喘患者声诊参数治疗前后有显著差异；哮喘患者经治疗后鼻塞等肺系症状出现的频率减少；哮喘患者治疗前后脉象参数差异不显著。哮喘患者治疗后FEV1.0%升高，说明哮喘患者通气功能得到一定程度的改善。结论：中医四诊客观化检测可为支气管哮喘中医证候诊断、病情演变观察以及临床疗效评价提供有效的依据。
This study was aimed to observe bronchial asthma patients in remission after treatment of traditional Chi-nese medicine（TCM） with four diagnostic information, syndrome differentiation and changes oflung function indicators, in order to explore the efficacy evaluation with TCM characteristics. TCM tongue manifestation instrument, TCM in-quiry scale, pulse-taking instrument, acoustic diagnostic information collection system, and spirometer were used in thecollection of 33 bronchial asthma cases in remission before and after treatment （1~5 months） basedon four diagnos-tic information and lung function indexes. Single-factor analysis of variance and other methods were used in the analysis of four diagnostic parameters and lung function indexes before and after treatment. The results showed that after TCM treatment, there were significant changes on indexes such as facial complexion, tongue sub-region color, color of tongue coating and other parameters. There was significant difference in the acoustic parameters before and after treatment. After TCM treatment, the frequency of lung system symptom such as nasal obstruction was decreased. There was no significant difference on changes of pulse-taking indexes among asthma patients before and after treat-ment. After treatment, the FEV1.0% of asthma patients was increased,whichindicated that asthma ventilatory function had been improved to some extent. It was concluded that TCM objective test provide an effective basis for the diag-nosis of bronchial asthma on aspects such as TCM syndrome, disease change observation and clinical evaluation.
出处
《世界科学技术-中医药现代化》
北大核心
2014年第6期1294-1299,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委面上项目(81173199):基于中医四诊信息融合的常见中医证候诊断模型研究
负责人:王忆勤
上海市卫生局中医药事业发展三年行动计划(重大研究)项目(ZYSNXD-CC-ZDYJ012):中医临床四诊技能训练与考核系统研制
负责人:王忆勤
上海市科学技术委员会中医药国际标准培育项目(ZYSNXD-CC-BZH):中医舌象图像
参数国际标准的前期研究
负责人:王忆勤
国家中医药管理局开发提升改造项目(ZYZLSB-2012[022]):面向健康监测的物联网系统的开发
负责人:王忆勤
上海市教育委员会高校青年教师培养资助计划项目(ZZszy13003):支气管哮喘证候模型及其与免疫指标的相关性研究
负责人:徐琎
关键词
哮喘
中医
四诊信息
肺功能
Asthma
traditional Chinese medicine
four diagnostic information
lung function
