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三维适形与普通同期放化疗对Ⅲ期非小细胞肺癌疗效观察 被引量:6

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摘要 目的观察和比较三维适形同期放化疗与普通同期放化疗治疗Ⅲ期非小细胞肺癌患者的近期疗效和耐受性。方法回顾性选取100例Ⅲ期非小细胞肺癌患者,按照治疗方法的不同,分为普通放疗组与三维适形组。普通放疗组给普通放疗+DP方案化疗,三维适形组给予三维适形放疗+DP方案化疗,观察两组患者经治疗后的近期疗效及副反应的发生情况。结果两组患者近期疗效率三维适形组高于普通放疗组,但差异无统计学意义(P>0.05);食管及肺放射性损伤发生率三维适形组均低于普通放疗组(P<0.05);放疗40 Gy时、放疗结束时和结束1月后肌钙蛋白水平三维适形组均低于普通放疗组(P<0.05)。结论三维适形同期放化疗与普通同期放化疗对Ⅲ期非小细胞肺癌疗效相似,但引起较少的食管、肺放射性损伤以及心脏损害,耐受性好,值得临床推广使用。
作者 莫清华
出处 《中南医学科学杂志》 CAS 2014年第5期491-493,共3页 Medical Science Journal of Central South China
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