摘要
目的 :探讨胃癌患者术前免疫水平与病情及预后的关系。 方法 :通过术前检测胃癌患者 NK细胞活性 (乳酸脱氢酶释放法 )及 T细胞亚群 (FACS法 )的水平 ,结合术中发现、术后病理结果以及临床随访结果进行研究。结果 :与对照组相比 ,胃癌患者术前免疫功能明显降低 ,且其免疫水平与病期呈显著负相关 ,与预后呈正相关。结论 :肿瘤患者术前免疫功能的测定对术前病情的估计、预后的判断有重要的指导意义。
Objective: To explore the relationship between the preoperative immune state and the progress, the prognosis in patients with gastric carcinoma. Methods: The NK cell activity (lactdehydrogenase releasing),the level of T cells subgroup (FACS) were detected preoperatively. The data of intra operative findings, pathologic observations and the results of clinical follow up were also studied. Results: The preoperative immune function in cancer patients was significantly reduced compared with the control group, and it had a significantly negative correlation with the stage of the cancer, but a positive correlation with the prognostic results. Conclusion: The detection of the preoperative immune state can play an important role in the estimation of the disease progress and the prognosis in cancer patients.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2002年第7期752-754,共3页
Academic Journal of Second Military Medical University
