转基因小鼠技术及其在肿瘤研究中的应用
Transgenic Mice Technology and its Application in Tumor Research
摘要
本文综述了近年来出现的一些转基因新方法 ,诸如精子载体法、核移植法及逆转录病毒法等 。
This paper reviewed the research progress of some novel transgenic methods, such as sperm mediated methods, nucleus transplantation methods and retrovirus mediated methods, and introduced application of transgenic mice technology in tumor research as well.
出处
《动物医学进展》
CSCD
2002年第4期46-49,共4页
Progress In Veterinary Medicine
参考文献24
-
1[1]Gordon J W, Scangos G A, Plotkin D J, et al. Genetic transformation of mouse embryos by microinjection of purified DNA[J]. Proc Natl Acad Sci U S A, 1980,77(12):7380～7384.
-
2[2]Isola L M, Gordon J W. Transgenic animals: a new era in developmental biology and medicine[J]. Biotechnology ,1991,16:3～20.
-
3[3]Adams J M, Harris A W, Pinkert C A, et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice[J]. Nature ,1985,318(6046):533～538.
-
4[4]Murphy D , Carter D A. Transgenisis techniques, Principles and Protocols[M]. Human Press.
-
5[5]Lavitrano M, Camaioni A, Fazio V M, et al. Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice[J]. Cell,1989,57(5):717～723.
-
6[6]Perry A C, Wakayama T, Kishikawa H, et al. Mammalian transgenesis by intracytoplasmic sperm injection[J]. Science ,1999,284(5417):1180～1183.
-
7[7]Lai L X, Huang WM , Qiao G L, et al. Generation of transgenic mice expressing human tissue-type plasminogen activator in mammary gland by transfecting spermatogonia in vivo[J]. Chinese Journal of animal anthology ,1997,11:16.
-
8[8]Kim J H, Jung-Ha H S, Lee H T. Development of a positive method for male stem cell mediated gene transfer in mouse and pig[J]. Mol Reprod Dev ,1997,46:515～526.
-
9[9]Schnieke A E, Kind A J, Ritchie W A, et al. Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts[J]. Science ,1997,278(5346):2130～2133.
-
10[10]Cibelli J B, Stice S L, Golueke P J, et al. Cloned transgenic calves produced from nonquiescent fetal fibroblasts[J]. Science ,1998,280(5367):1256～1258.
-
1陈林(综述),赵玲(综述).转基因小鼠技术与HIF-1α功能的研究[J].国外医学（生理病理科学与临床分册）,2004,24(2):132-135. 被引量：3
-
2杨玉芳,丁彦青.转基因小鼠技术在肿瘤研究中的应用与进展[J].医学综述,2004,10(1):1-3. 被引量：2
-
3何学令,尹海林.转基因小鼠技术中获得原核期受精卵最适时间的研究[J].四川动物,2004,23(4):341-343. 被引量：1
-
4王继英,杜立新.转基因动物制作及提高外源基因表达的策略[J].中国畜牧兽医,2002,29(2):30-34. 被引量：13
-
5发育生物学[J].中国学术期刊文摘,2006,12(21):132-132.
-
6周丽君.人源抗体在肿瘤治疗中的应用[J].海军总医院学报,2003,16(2):97-101.
-
7吴迪.小鼠早期胚胎发育和胚胎移植的改良[J].经济技术协作信息,2010(33):93-93.
-
8刘龙.肿瘤放射免疫治疗药物进展[J].铁道医学,2002,30(1):68-70. 被引量：2
-
9刘文献.转基因动物技术研究综述[J].生物技术,2003,13(4):39-41. 被引量：2
-
10沈子龙,廖建民,徐寒梅.转基因动物技术与转基因动物制药[J].中国药科大学学报,2002,33(2):81-86. 被引量：22
