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毛细管电泳-短小串联重复序列多态性方法及对人凝血因子BSTR位点的检测 被引量：1

PCR Typing of F B Short Tandem Repeat Polymorphism by Capillary Electrophoresis
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摘要 为开展高效毛细管电泳技术对STR位点的检测 ,通过建立毛细管电泳 短小串联重复序列 (STRs)多态性的检测方法 ,实现了利用毛细管电泳快速检测人凝血因子B (F13B)STR位点PCR产物的长度多态性 ,结果F13B STR基因型分型正确 ,图谱清晰 .方法的建立可简化常规多态性检测 ,实现快速。 The FB short tandem repeat(STR) alleles, four base pair difference in length, could be separated and identified by capillary gel electrophoresis(CGE).The gene types of these alleles were determined by runing with them a known length DNA fragment. This study paved the way for gene typing of STR locus or individual identification by capillary electrophoresis.
作者 裴黎 邓华 张丽君 姜成涛 赵兴春 常彩琴 王俭
机构地区 公安部物证鉴定中心 天津市口腔医院
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2002年第3期460-463,共4页 Progress In Biochemistry and Biophysics
基金 公安部重点课题基金资助 (9982 2 14 0 3 )~~
关键词 毛细管电泳-短小串联重复序列多态性方法 人凝血因子Ⅻ BSTR位点 检测 short tandem repeat, FB, capillary electrophoresis
分类号 Q987.2 [生物学—遗传学] D919.2 [医药卫生—法医学]
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参考文献12

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二级参考文献4

共引文献8

同被引文献7

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生物化学与生物物理进展
2002年 第3期

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