摘要
目的 研究血浆中血栓前体蛋白 (Tp P)的检测与心肌梗死的关系。方法 利用酶联免疫分析法测定 30例健康对照组和 4 8例患病组血浆中前体蛋白的水平。结果 患病组中心肌梗死患者 (n=35 )血浆 Tp P水平为 (8.132± 3.0 2 8)μg/ m l;其中男性为 (8.32 5± 3.35 8)μg/ m l,显著高于健康男性 (P<0 .0 1) ,女性为 (7.6 84±2 .987) μg/ ml,显著高于健康女性 (P<0 .0 1)。对照组 (n=30 )血浆 Tp P水平为 (2 .875± 0 .975 ) μg/ ml,其中男性为(3.0 14± 1.135 ) μg/ ml,女性为 (2 .738± 0 .895 ) μg/ ml,男女之间差异无显著性 (P>0 .0 5 )。统计学处理表明对照组与心肌梗死组差异有显著性 (P<0 .0 1)。结论 心肌梗死患者血浆 Tp P水平显著高于正常人 ,血浆 Tp P水平可作为诊断心肌梗死的一项敏感指标 。
Objective To study the relationship between thrombus precursor protein(TpP)and myocardial infarction.Methods The level of TpP in 48 patients were detected with ELISA,and compared with 30 healthy people as control.Results TpP level of myocardial infarction patients( n =35) was (8.132±3.028) μg/ml(male:8.325±3.358 μg/ml;femal:7.684±2.987 μg/ml).TpP level of health control( n =30) was 2.875±0.975 μg/ml(male:3.014±1.135 μg/ml,female:2.738±0.895 μg/ml).Statical anslysis showed TpP level of myocardial infarction patients was significantly higher than that in normal control( P <0.01).TpP levels in male and female patients was both higher than that in healthy male and female ( P < 0.01 )respectively.It showed no significantly difference between normal male and female( P <0.05).Conclusion TpP level of myocardil infarction patients was significantly higher than that in normal people.TpP may severe as a sensitive diagnostic indecator of myocardial infarction,and it may direct early dissolving embolus treatment of myocardial infarction.
出处
《淮海医药》
2002年第3期189-190,共2页
Journal of Huaihai Medicine
